5732-97-8

Usage

Uses

Used in Pharmaceutical Industry:
2-Oxabicyclo[2.2.1]heptan-3-one is used as a precursor in the synthesis of various pharmaceuticals for its ability to be easily modified to create different derivatives with specific applications.
Used in Agrochemical Industry:
2-Oxabicyclo[2.2.1]heptan-3-one is utilized as a starting material in the production of agrochemicals, contributing to the development of effective and targeted pest control solutions.
Used in Fragrance Industry:
2-Oxabicyclo[2.2.1]heptan-3-one is employed as a building block in the creation of fragrances, leveraging its reactivity to produce a variety of scent compounds.
Used in Fine Chemicals Production:
As a valuable intermediate, 2-Oxabicyclo[2.2.1]heptan-3-one is used in the production of fine chemicals, which are essential in various specialized applications across different industries.

Upstream product

• 1092973-97-1 6-bromo-2-oxabicyclo[2.2.1]heptan-3-one 
• 7686-77-3 3-cyclopentene-1-carboxylic acid 
• 16442-39-0 Bicyclo<2.1.1>hexanon-(5) 
• 32811-76-0 3-hydroxycyclopentanecarboxylic acid methyl ester 
• 32811-75-9 methyl 3-oxocyclopentane-1-carboxylate 
• 55843-47-5 (+/-)-cis-3-hydroxy-cyclopentanecarboxylic acid 

Downstream Products

• 128095-32-9 (±)-cis-benzyl 3-hydroxycyclopentane-1-carboxylate 
• 1110772-09-2 cis-3-(aminomethyl)cyclopentan-1-ol 
• 1007306-65-1 N-Boc cis-3-(aminomethyl)cyclopentan-1-ol 

Relevant academic research and scientific papers

RECYCLABLE POLYMERS BASED ON RING-FUSED GAMMA-BUTYROLACTONES

The invention discloses a class of new polymers, trans-ring-fused poly(4-hydroxybutyrate)s (RF-P4HB) that exhibit a unique set of properties, including robust thermal stability and mechanical strength, quantitative recyclability to the building block monomers via thermolysis and/or chemical catalysis, and convenient production from the chemical ring-opening polymerization under ambient temperature and pressure. Another unique property is the formation of crystalline stereocomplexed polymers with high melting temperature upon mixing the two enantiomeric RF-P4HB chains via stereocomplexing co-crystallization. This invention also provides the corresponding ring-fused lactone monomer structures that enable the synthesis of the RF-P4HB polymers, through trans-fusing of rings to the parent γ-butyrolactone ring. Furthermore, a polymerization or copolymerization process for the synthesis of RF-P4HB polymers and copolymers is disclosed.

METABOLITES OF THE JANUS KINASE INHIBITOR (R)-3-(4-(7H-PYRROLO[2,3-d]PYRIMIDIN-4-YL)-1H-PYRAZOL-1-YL)-3-CYCLOPENTYLPROPANENITRILE

The present invention provides active metablites of 3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.

On the possibility of carbamate-directed hydroboration. An approach to the asymmetric synthesis of 1-aminocyclopentane-1,3-dicarboxylic acid

Hydroboration (using BH3) of 1-substituted 3-cyclopentenes 3, 9 and 17 and an enantioselective synthesis of the excitatory amino acid 1- aminocyclopentane-1,3-dicarboxylic acid via asymmetric hydroboration [90% de, 45% ee using (+)-IpcBH2] of cyclopentene 17 are described.

Stereoselective conversion of tetraalkyltin compounds to alcohols

A stereoselective method for the conversion of a tributyltin group at an unactivated carbon atom has been achieved. Reaction with bromine leads to preferential cleavage of a butyl group, giving an alkylbromodibutylstannane. Subsequent reaction with basic peroxide leads to preferential cleavage of the more-substituted carbon-tin bond and formation of the corresponding alcohol with retention of configuration.