57324-83-1Relevant articles and documents
3-Substituted-1,2-benzisoxazoles and pharmaceutically acceptable acid addition salts thereof
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, (2008/06/13)
3-Substituted-1,2-benzisoxazole derivative of the following formula: SPC1 Wherein R1 is hydrogen, hydroxy, nitro, alkyl, alkoxy, halogen or amino; R2 is hydroxyamino, amino, hydrazino, mono- or di- alkyl substituted amino, aralkylamino, acyloxyamino, morpholino, piperazine which is unsubstituted or substituted with alkyl, aralkyl or aryl at 4 position, or pyrrolidino, or R2 may combine with imino group and form together with the adjacent carbon atom a heterocyclic ring such as imidazoline or tetrahydropyrimidine; and n is an integer of 0 to 3, and its pharmaceutically acceptable acid addition salt, and preparation thereof. The present compounds show valuable pharmacological properties, such as anti-reserpine activity, central nervous depressing activity, anti-hypertensive activity and l-dopa potentiating activity.