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1(2H)-Pyridinecarboxylic acid, 3,4-dihydro-4-oxo-, ethyl ester, also known as 1-(Ethoxycarbonyl)-1,2,3,4-tetrahydro-4-oxopyridine, is an organic compound that serves as a valuable synthetic intermediate in the pharmaceutical industry. It is characterized by its unique chemical structure, which includes a pyridine ring and an ester functional group, making it a versatile molecule for various chemical reactions and applications.

57330-84-4

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57330-84-4 Usage

Uses

1. Used in Pharmaceutical Synthesis:
1(2H)-Pyridinecarboxylic acid, 3,4-dihydro-4-oxo-, ethyl ester is used as a synthetic intermediate for the development of various pharmaceutical compounds. Its unique structure allows it to be a key component in the synthesis of complex molecules with potential therapeutic applications.
2. Used in the Synthesis of E902770:
In the pharmaceutical industry, 1(2H)-Pyridinecarboxylic acid, 3,4-dihydro-4-oxo-, ethyl ester is used as a synthetic intermediate for the synthesis of (E)-Ethyl 4-(8-chloro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(6H)-ylidene)-3,4-dihydropyridine-1(2H)-carboxylate (E902770), a compound with potential applications in drug development.
3. Used as an Impurity in Loratadine Synthesis:
1(2H)-Pyridinecarboxylic acid, 3,4-dihydro-4-oxo-, ethyl ester is also an impurity in the synthesis of Loratadine (L469575), a nonsedating-type histamine H1-receptor antagonist used to treat allergies and other conditions. Its presence in the synthesis process highlights the importance of controlling impurities to ensure the safety and efficacy of the final product.

Check Digit Verification of cas no

The CAS Registry Mumber 57330-84-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,3,3 and 0 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 57330-84:
(7*5)+(6*7)+(5*3)+(4*3)+(3*0)+(2*8)+(1*4)=124
124 % 10 = 4
So 57330-84-4 is a valid CAS Registry Number.

57330-84-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 4-oxo-2,3-dihydropyridine-1-carboxylate

1.2 Other means of identification

Product number -
Other names 1-ethoxycarbonyl-2,3-dehydro-4-piperidone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:57330-84-4 SDS

57330-84-4Relevant academic research and scientific papers

Synthesis of Novel Iminosugar Derivatives Based on a 2-Azabi-ccyclo[41.0]heptane Skeleton

López-Rodríguez, Alberto,Domínguez, Gema,Pérez-Castells, Javier

, p. 4606 - 4612 (2017/10/16)

Iminosugars are good starting points for the development of different kinds of drugs. Many are polyhydroxylated piperidines that behave as biomimetics of their corresponding pyranoses analogues. In the interaction with carbohydrate processing enzymes, sel

Catalytic enantioselective conjugate addition of dialkylzinc reagents to N-substituted-2,3-dehydro-4-piperidones

Sebesta, Radovan,Pizzuti, Maria Gabriella,Boersma, Arnold J.,Minnaard, Adriaan J.,Feringa, Ben L.

, p. 1711 - 1713 (2007/10/03)

The first, highly enantioselective, copper/phosphoramidite-catalyzed conjugate addition of dialkylzinc reagents to N-substituted 2,3-dehydro-4- piperidones is described. The Royal Society of Chemistry 2005.

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