57338-10-0

Upstream product

• 17351-28-9 1,2-dimethyl-1,4-cyclohexadiene 

Downstream Products

• 137053-61-3 C₁₈H₁₇NO₃ 
• 100164-23-6 (1S^*,10R^*)-10-Hydroxy-1,10-dimethyl-4-phenyl-2,4,6-triazatricyclo<5.2.2.0^2,6>undec-8-en-3,5-dion 
• 100084-51-3 (1S^*,10S^*)-10-Hydroxy-1,10-dimethyl-4-phenyl-2,4,6-triazatricyclo<5.2.2.0^2,6>undec-8-en-3,5-dion 

Relevant academic research and scientific papers

A Halide-Free Method for Olefin Epoxidation with 30% Hydrogen Peroxide

A catalytic system consisting of sodium tungstate dihydrate, (aminomethyl) phosphonic acid, and methyltrioctylammonium Hydrogensulfate, effects the epoxidation of olefins using 30% hydrogen peroxide with a substrate-to-catalyst molar ratio of 50 - 500. The reaction proceeds in high yield without solvents, or, alternatively, with added toluene under entirely halide-free conditions. Lipophilic ammonium hydrogensulfate, which replaces the conventional chloride, and an (α-aminoalkyl)phosphonic acid are crucial for the high reactivity. This method is operationally simple, environmentally benign, and much more economical than the oxidation with m-chloroperbenzoic acid, allowing for a large-scale preparation of epoxides. Various substrates including terminal olefins, 1,1- and 1,2-disubstituted olefins, cyclic olefins, and tri- and tetrasubstituted olefins as well as allylic alcohols, esters, α,β-unsaturated ketones, and ethers can be epoxidized in high yield. The scope and limitations of this new reaction system are discussed.