57338-21-3Relevant academic research and scientific papers
Pyrazolo[3,4-b]pyridine in heterocyclic synthesis: Synthesis of new pyrazolo[3,4-b]pyridines, imidazo[1′,2′:1,5]pyrazolo[3,4-b] pyridines, and pyrido[2′,3′:3,4]pyrazolo[1,5-a]pyrimidines
Gad-Elkareem, Mohamed A. M.,Abdel-Fattah, Azza M.,Elneairy, Mohamed A. A.
, p. 592 - 599 (2008/02/12)
Pyrazolo[3,4-b]pyridine derivatives 7 and 9 were synthesized via the reaction of 3-amino-1H-pyrazolo-[3,4-b]pyridine derivative 2 with ω-bromoacetophenones. Reaction of 7 and 9 with Ac2O afforded the imidazo[1′,2′:1,5]pyrazolo[3,4-b]pyridine derivative 8 and pyrazolo[3,4-b]pyridine derivative 10, respectively. Reaction of 2 with chloroacetonitrile followed by DMF-DMA gave imidazo[1′,2′:1,5] pyrazolo[3,4-b]pyridines 4 and 5, respectively. Acetylacetone and 1,1-dicyano-2,2-dimethylthioethene were reacted with 2 to afford the pyrido[2′,3′:3,4]pyrazolo-[1,5-a]-pyrimidines 11 and 14, respectively. Also, 2 reacted with DMF-DMA to yield the formamidine 15, which in turn, reacted with active methylene reagents, yielding the corresponding pyrido[2′,3′:3,4]pyrazolo[1,5-a]pyrimidines 18 and 23a-23d.
Process for the preparation of aminomethylene compounds
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, (2008/06/13)
Aminomethylene compounds of the formula STR1 can be prepared by reaction of C-H-acid compounds of the formula STR2 with salts of the formula STR3 in the presence of simple inorganic bases, where the radicals R1 to R4, R7, R8 and X? have the meanings given in the description.
