57371-40-1

Basic information

• Product Name: 1-Nitrosopyrrolidine-d4
• Synonyms: 1-Nitrosopyrrolidine-d4;N-Nitrosopyrrolidine-d4;NPYR-d4;NSC 18797-d4;2,2,5,5-tetradeuterio-1-nitrosopyrrolidine
• CAS NO: 57371-40-1
• Molecular Formula: C4H8N2O
• Molecular Weight: 100.11912
• Product Categories: Isotope Labelled Compounds;Mutagenesis Research Chemicals;Nitric Oxide Reagents;Isotope Labelled Compounds, Mutagenesis Research Chemicals, Nitric Oxide Reagents
• Mol File: 57371-40-1.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Soluble), Ethyl Acetate (Slightly), Methanol (Sparingly)
• CAS DataBase Reference: 1-Nitrosopyrrolidine-d4(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Nitrosopyrrolidine-d4(57371-40-1)
• EPA Substance Registry System: 1-Nitrosopyrrolidine-d4(57371-40-1)

Safety Data

• Hazardous Substances Data: 57371-40-1(Hazardous Substances Data)

Usage

Description

1-Nitrosopyrrolidine-d4, also known as N545950, is an isotopically labeled N-nitroso compound (NOC) that has been identified as a potential contributor to human colon carcinogenesis. However, the toxicological mechanisms behind its carcinogenic effects have not been fully understood. It is a yellow oil and is listed as a drinking water contaminant candidate on the United States Environmental Protection Agency (EPA) list, which focuses on environmental and food contaminants.

Uses

Used in Environmental and Food Contaminant Research:
1-Nitrosopyrrolidine-d4 is used as a research compound for studying the effects of N-nitroso compounds on human health, particularly in the context of colon carcinogenesis. Its application in this field is crucial for understanding the toxicological mechanisms involved and for developing strategies to mitigate the risks associated with these contaminants.
Used in Toxicological Studies:
1-Nitrosopyrrolidine-d4 is used as a toxicological research tool to investigate the mechanisms of toxicity and carcinogenicity of N-nitroso compounds. This helps in the development of preventive measures and potential treatments for diseases associated with exposure to these contaminants.
Used in Analytical Chemistry:
As an isotopically labeled compound, 1-Nitrosopyrrolidine-d4 can be used in analytical chemistry for the detection and quantification of N-nitroso compounds in various samples, such as environmental and food samples. This aids in monitoring and controlling the levels of these contaminants to ensure safety and compliance with regulatory standards.
Used in Pharmaceutical Research:
1-Nitrosopyrrolidine-d4 may also be used in the pharmaceutical industry for the development of drugs targeting N-nitroso compounds or their associated pathways. Understanding the mechanisms of action and potential interactions with other compounds can lead to the creation of more effective treatments for diseases related to these contaminants.