5738-24-9Relevant articles and documents
Semi-synthetic isoflavones as BACE-1 inhibitors against Alzheimer's disease
Ribaudo, Giovanni,Coghi, Paolo,Zanforlin, Enrico,Law, Betty Yuen Kwan,Wu, Yuki Yu Jun,Han, Yu,Qiu, Alena Congling,Qu, Yuan Qing,Zagotto, Giuseppe,Wong, Vincent Kam Wai
, p. 474 - 483 (2019/03/29)
BACE-1 is considered to be one of the targets for prevention and treatment of Alzheimer's disease (AD). We here report a novel class of semi-synthetic derivatives of prenylated isoflavones, obtained from the derivatization of natural flavonoids from Maclu