(+/-)-17β-Hydroxy-8α-estr-5(10)-en-3-one, also known as 8α-estradiol, is a naturally occurring steroid hormone derived from the parent compound estradiol. It is a chiral molecule, meaning it exists in two non-superimposable mirror image forms, (+) and (-), which are referred to as enantiomers. (+/-)-17β-Hydroxy-8α-estr-5(10)-en-3-one plays a crucial role in the regulation of various physiological processes, including the development and maintenance of female secondary sexual characteristics, as well as the modulation of the menstrual cycle and pregnancy. 8α-estradiol is synthesized in the body from cholesterol and is involved in the regulation of gene expression, cellular proliferation, and differentiation. Due to its significant impact on human health and development, research on 8α-estradiol and its derivatives is essential for understanding the underlying mechanisms of various hormonal disorders and potential therapeutic applications.
The CAS Registry Mumber 5738-57-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,7,3 and 8 respectively; the second part has 2 digits, 5 and 7 respectively. Calculate Digit Verification of CAS Registry Number 5738-57: (6*5)+(5*7)+(4*3)+(3*8)+(2*5)+(1*7)=118 118 % 10 = 8 So 5738-57-8 is a valid CAS Registry Number.
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