57382-44-2

Usage

Derivative of naphthalene

yes

Type of compound

amine

Contains nitrogen atom

yes

Bonded to hydrogen atoms

yes

Presence of methoxy group

yes (indicates a methyl group bonded to an oxygen atom)

Unique chemical properties

yes

Used in industrial and research applications

yes

Synthesis of pharmaceuticals

yes

Synthesis of agrochemicals

yes

Hazardous properties

may have

Proper safety protocols

should be used in accordance with

Upstream product

• 77029-01-7 6-methoxy-[1]naphthonitrile 

Downstream Products

• 98977-62-9 (E)-N-methyl-N-(3-phenyl-2-propenyl)-6-methoxy-1-naphthalenemethanamine 
• 1071127-07-5 (6-Methoxy-naphthalen-1-ylmethyl)-((E)-3-phenyl-allyl)-amine 

Relevant academic research and scientific papers

Examination of the role of the acidic hydrogen in imparting selectivity of 7-(aminosulfonyl)-1,2,3,4-tetrahydroisoquinoline (SK and F 29661) toward inhibition of phenylethanolamine N-methyltransferase vs the α2-adrenoceptor

7-(Aminosulfonyl)-1,2,3,4-tetrahydroisoquinoline (SK and F 29661, 1) is a potent inhibitor of the enzyme phenylethanolamine N-methyltransferase (PNMT, EC 2.1.1.28). In contrast to other inhibitors of PNMT, it is also highly selective toward PNMT in compar

Synthesis and Structure-Activity Relationships of Naftifine-Related Allylamine Antimycotics

Naftifine (1) is the first representative of the new antifungal allylamine derivatives.Its biological activity is strictly bound to specific structural requirements that are unrelated to those of known antifungals.A tertiary allylamine function seems to be a prerequisite for activity against fungi.By systematic variation of the individual structural elements in 1, detailed structure-activity relationships are defined in which the phenyl ring is the structural feature permitting the widest variations.Versatile synthetic routes to allylamine derivatives and comparative biological data are presented.