57391-73-8Relevant academic research and scientific papers
Regioselective synthesis and antitumor screening of some novel N-phenylpyrazole derivatives
Farag, Ahmad M.,Mayhoub, Abdelrahman S.,Barakat, Saber E.,Bayomi, Ashraf H.
, p. 881 - 889 (2008/09/18)
The versatile, hitherto unreported 4-acetyl-5-methyl-1-phenyl-3-phenylcarbamoyl-1H-pyrazole (3) was prepared via the reaction of 2-(2-phenylhydrazono)-2-chloro-N-phenylacetamide with pentan-2,4-dione in the presence of sodium ethoxide. Reaction of 3 with
1,3-Dipolar Cycloaddition of Four Hydrazonoyl Chlorides to β-Diketones and α,β-Unsaturated Ketones
Albar, Hassan A.
, p. 872 - 889 (2007/10/03)
The 1,3-dipolar cycloaddition of four hydrazonoyl chloride derivatives with the sodium salt of unsymmetrical β-diketones (benzoylacetone) offers a versatile method for the regioselective synthesis of 2H-pyrazoles in a similar fashion to the cycloaddition of the nitrilimides with α,β-unsaturated ketones and esters. The structures of the prepared isomeric pyrazole and pyrazoline derivatives were established by spectroscopic and chemical methods.
