573976-85-9

Basic information

• Product Name: (R)-3-((S)-4-Benzyl-2-oxo-oxazolidine-3-carbonyl)-5-methyl-hexanoic acid
• Synonyms: (R)-3-((S)-4-Benzyl-2-oxo-oxazolidine-3-carbonyl)-5-methyl-hexanoic acid
• CAS NO: 573976-85-9
• Molecular Weight: 333.384
• Mol File: 573976-85-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-3-((S)-4-Benzyl-2-oxo-oxazolidine-3-carbonyl)-5-methyl-hexanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-((S)-4-Benzyl-2-oxo-oxazolidine-3-carbonyl)-5-methyl-hexanoic acid(573976-85-9)
• EPA Substance Registry System: (R)-3-((S)-4-Benzyl-2-oxo-oxazolidine-3-carbonyl)-5-methyl-hexanoic acid(573976-85-9)

Safety Data

• Hazardous Substances Data: 573976-85-9(Hazardous Substances Data)

Upstream product

• 113543-30-9 (S)-4-benzyl-3-(4-methylpentanoyl)oxazolidin-2-one 
• 144287-83-2 (R)-tert-butyl 3-((S)-4-benzyl-2-oxooxazolidine-3-carbonyl)-5-methylhexanoate 

Downstream Products

• 573976-86-0 (R)-1-((S)-4-Benzyl-2-oxo-oxazolidin-3-yl)-2-isobutyl-4-morpholin-4-yl-butane-1,4-dione 

Relevant articles and documents

Improved gelatinase a selectivity by novel zinc binding groups containing galardin derivatives

The synthesis of several analogues of galardin, a MMP inhibitor, are presented with their in vitro inhibitory activity against MMP-1 and MMP-2. These compounds contain a distinct Zinc Binding Group (ZBG). Those having a 2-acylated-heterocycle as well as a 2-arylamide function do not exhibit a good inhibition/selectivity against the enzymes tested. On the contrary, those that are based on a hydrazide scaffold present potent selectivity for MMP-2 versus MMP-1.