573983-71-8

Upstream product

• 166900-19-2 C₁₅H₂₄O 
• 573969-75-2 (4aS,8aS)-8-(2,5-Dimethoxy-benzyl)-4,4,7,8a-tetramethyl-1,2,3,4,4a,5,6,8a-octahydro-naphthalene 
• 573969-74-1 (2,5-Dimethoxy-phenyl)-((4aS,8aS)-2,5,5,8a-tetramethyl-3,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl)-methanol 
• 124377-31-7 (+)-[(4aS,8aS)-2,5,5,8a-tetramethyl-3,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]methanol 
• 68985-10-4 (4aS,8aS)-3,4,4a,5,6,7,8,8a-octahydro-2,5,5,8a-tetramethylnaphthalene-1-carboxaldehyde 
• 58795-27-0 (4aS,8aS)-1,1,4a-Trimethyl-5,6-dimethylene-decahydro-naphthalene 

Downstream Products

• 1376654-34-0 (+)-yahazunone 

Relevant academic research and scientific papers

Divergent Synthesis of Bioactive Marine Meroterpenoids by Palladium-Catalyzed Tandem Carbene Migratory Insertion

The divergent synthesis of (+)-8-epi-puupehedione, (+)-chromazonarol, (+)-yahazunol, and (+)-yahazunone has been accomplished. The key steps were a palladium-catalyzed tandem carbene migratory insertion of an aryl iodide and a drimanal hydrazone, a highly regioselective enol reduction, an oxa-Stork–Danheiser transposition reaction, an electrocyclization of a conjugated tetraenone, and a redox reaction of dimethoxybenzenes.

An efficient method for the synthesis of (+)-cyclozonarone, isozonarol δ,8,9 and isozonarone δ8,9

An efficient method for the synthesis of (+)-cyclozonarone 5, isozonarol Δ8,9 6 and isozonarone Δ8,9 7 via the diene 4, obtained in two steps from manool 3, is described.