57409-29-7Relevant academic research and scientific papers
Metal-free amidation of carboxylic acids with tertiary amines
Phakhodee, Wong,Wangngae, Sirilak,Pattarawarapan, Mookda
, p. 60287 - 60290 (2016/07/11)
A direct amidation of carboxylic acids with tertiary amines could be carried out in the presence of the Ph3P-I2 activator. With an appropriate reagent addition sequence, a range of carboxylic acids including aliphatic, allylic, and aromatic acids could be converted into their corresponding tertiary amides under mild conditions without requirement of metal catalysis.
