57411-91-3

Usage

Uses

Used in Pharmaceutical Industry:
(4-hydrazinophenyl)acetonitrile is used as a building block for the synthesis of various drugs, including anti-cancer and anti-inflammatory medications, due to its versatile chemical properties and reactivity.
Used in Chemical Industry:
(4-hydrazinophenyl)acetonitrile is used as a precursor in the production of dyes, pigments, and other specialty chemicals, contributing to the development of a diverse range of products.
Used in Materials Science:
(4-hydrazinophenyl)acetonitrile is used as a research compound for exploring its potential in developing new materials with unique properties, expanding its applications in various fields.

InChI:InChI=1/C8H9N3/c9-6-5-7-1-3-8(11-10)4-2-7/h1-4,11H,5,10H2

Upstream product

• 3544-25-0 p-aminophenylacetonitrile 

Downstream Products

• 288621-65-8 5'-acetamidinoethylnaltrindole 
• 126274-41-7 [4-(1-Oxy-benzotriazol-2-yl)-phenyl]-acetic acid 
• 126274-54-2 [4-(1-Oxy-benzotriazol-2-yl)-phenyl]-acetonitrile 
• 126274-52-0 {4-[N'-(2-Nitro-phenyl)-hydrazino]-phenyl}-acetonitrile 
• 126274-55-3 [4-(1-Oxy-6-trifluoromethyl-benzotriazol-2-yl)-phenyl]-acetonitrile 

Relevant academic research and scientific papers

Triazole containing indole derivatives

A class of substituted imidazole, triazole and tetrazole derivatives are selective agonists of 5-HT 1 -like receptors and are therefore useful in the treatment of clinical conditions, in particular migraine and associated disorders, for which a selective agonist of these receptors is indicated.

Indole-5-acetamides for treatment of migraine

Compounds are disclosed of general formula (I): STR1 wherein R1, R3, R4, R6 and R7, which may be the same or different, each represents a hydrogen atom or an alkyl group; R2 represents a hydrogen atom or an alkyl, aryl, aralkyl, cycloalkyl or alkenyl group; or R1 and R2, together with the nitrogen atom to which they are attached, form a saturated monocyclic 5 to 7-membered ring which may optionally contain a further hetero function; R5 represents a hydrogen atom or an alkyl or alkenyl group; or R4 and R5 together form an aralkylidene group; Alk represents an alkylene chain containing two or three carbon atoms which may be unsubstituted or substituted by not more than two C1-3 alkyl groups; and X represents an oxygen or sulphur atom; and physiologically acceptable salts, solvates and bioprecursors thereof. The compounds are described as potentially useful for the treatment of migraine and may be formulated as pharmaceutical compositions in conventional manner using one or more pharmaceutically acceptable carriers or excipients. Various processes for the preparation of the compounds are disclosed including, for example, a process involving reacting an indole having an appropriate nitrile group at the 5-position, with a suitable oxygen- or sulphur-containing compound in order to introduce the required amide or thioamide group at the 5-position on the indole nucleus.