57428-53-2

Basic information

• Product Name: 4-allylcyclohexane-1,3-dione
• Synonyms: 4-allylcyclohexane-1,3-dione
• CAS NO: 57428-53-2
• Molecular Weight: 152.193
• Mol File: 57428-53-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4-allylcyclohexane-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 4-allylcyclohexane-1,3-dione(57428-53-2)
• EPA Substance Registry System: 4-allylcyclohexane-1,3-dione(57428-53-2)

Safety Data

• Hazardous Substances Data: 57428-53-2(Hazardous Substances Data)

Upstream product

• 23074-59-1 3-isobutoxycyclohex-2-en-1-one 
• 504-02-9 1,3-cylohexanedione 
• 106-95-6 allyl bromide 
• 40649-34-1 6-allyl-3-isobutoxycyclohex-2-en-1-one 

Downstream Products

• 99228-09-8 5-(1-Oxo-6-(2-propenyl)-2-cyclohexen-3-yl)amino-1-(2-chloroethyl)-4-cyanopyrazole 
• 369372-30-5 2-bromo-benzoic acid 4-allyl-3-oxo-cyclohex-1-enyl ester 
• 369372-29-2 2-bromo-benzoic acid 6-allyl-3-oxo-cyclohex-1-enyl ester 
• 369372-28-1 3-bromo-2,2-dimethyl-propionic acid 4-allyl-3-oxo-cyclohex-1-enyl ester 
• 81465-55-6 4-Allyl-3-iodo-cyclohex-3-enone 
• 81465-49-8 4-Allyl-3-iodo-cyclohex-2-enone 
• 81465-41-0 6-Allyl-3-iodo-cyclohex-2-enone 

Relevant articles and documents

Synthesis of 2,6-dioxo-1,2,3,4,5,6-hexahydroindoles by acid-catalyzed cyclization of acetal-protected (2,4-dioxocyclohex-l-yl)acetamides and their transformation into 5,8,9,10-tetrahydro-6H-indolo[2,1-a]isoquinolin-9-ones

Acetal-protected (2,4-dioxocyclohex-1-yl)-acetic acids were prepared by allylation of dilithiated 1,3-cyclohexane-1,3-diones, protection of the carbon-yl groups and oxidation of the alkene moiety. Their reaction with amines afforded the corresponding amides which were transformed, by acid-catalyzed cyclization, into various 2,6-dioxo-1,2,3,4,5,6-hexahy-droindoles. The reaction of the latter with triflic acid resulted in the formation of novel 5,8,9,10-tetrahy-dro-6H-indolo[2,1-a]isoquinolin-9-ones.

Free radical reactions for heterocycle synthesis. Part 5: Formation of novel bridged spirolactones by double cyclizations

Novel bridged spirolactones have been synthesized via double radical cyclization of enol ester radicals.

Pyrazolopyridine cycloalkanones and process for their preparation

Novel tetrahydropyrazolo-[3,4-b]quinolinones, cyclopenta[b]pyrazolo-[4,3-e]pyridinones and cyclohepta[b]-pyrazolo[4,3-e]pyridinones, useful as anxiolytics having reduced side effects, are disclosed, including methods of preparation, pharmaceutical compositions containing them and intermediates used in their preparation.