57443-82-0 Usage
Class
Dihydroxyaromatic ethers
Use
Research tool in neuroscience
Function
Blocks the activity of certain enzymes involved in the metabolism of neurotransmitters
Enzyme Inhibition
Inhibits poly(ADP-ribose) polymerase (PARP)
Role of PARP
Involved in DNA repair and cell survival
Potential Applications
Treatment of neurodegenerative diseases and cancer
Mechanism
Protects neurons from damage and inhibits the growth of cancer cells
Additional Properties
Investigated for anti-inflammatory and antioxidant properties
Therapeutic Applications
Versatile compound with potential use in various fields of medicine
Check Digit Verification of cas no
The CAS Registry Mumber 57443-82-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,4,4 and 3 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 57443-82:
(7*5)+(6*7)+(5*4)+(4*4)+(3*3)+(2*8)+(1*2)=140
140 % 10 = 0
So 57443-82-0 is a valid CAS Registry Number.
57443-82-0Relevant articles and documents
LATERAL METALLATION OF METHYLATED NITROGENOUS HETEROCYCLES
Kaiser, Edwin M.
, p. 2055 - 2064 (2007/10/02)
Me groups on nitrogenous heterocycles can be conveniently metallated by a variety of strongly basic reagents to afford synthetically useful carbanions.The negative charge of such anions resides predominantly on the ring N atoms.The site of lithiation on pyridines and quinolines bearing Me groups in both the 2- and 4-positions depends upon the ability of the ring N atom to complex with the metallating agents.Carbanions derived from methylated pyridines, quinolines, naphthyridines, isoquinolines, pyridocarbazoles, pteridines, pyridoindoles and quinoxalines are discussed.References are provided describing condensations of these reagents with a variety of both common and uncommon electrophiles.
