57463-01-1

Usage

Uses

Used in Organic Chemistry:
2-METHYL-6-NITRO-2H-BENZO[B][1,4]OXAZIN-3(4H)-ONE is used as a building block for the synthesis of various biologically active compounds, pharmaceuticals, and agrochemicals due to its unique structure and properties.
Used in Pharmaceutical Industry:
2-METHYL-6-NITRO-2H-BENZO[B][1,4]OXAZIN-3(4H)-ONE is used as an intermediate in the development of new pharmaceuticals, contributing to the creation of innovative drugs with potential therapeutic applications.
Used in Agrochemical Industry:
2-METHYL-6-NITRO-2H-BENZO[B][1,4]OXAZIN-3(4H)-ONE is used as a key component in the synthesis of agrochemicals, playing a crucial role in the development of new pesticides and other agricultural products.
Used in Material Science:
2-METHYL-6-NITRO-2H-BENZO[B][1,4]OXAZIN-3(4H)-ONE is used as a valuable intermediate for the development of new materials and chemical formulations, leveraging its unique chemical and physical properties to create innovative products in material science.

Upstream product

• 535-11-5 Ethyl 2-bromopropionate 
• 99-57-0 2-hydroxy-5-nitroaniline 
• 563-76-8 α-bromopropionyl bromide 

Downstream Products

• 52042-31-6 4-(2,3-dihydroxy-propyl)-2-methyl-6-nitro-4H-benzo[1,4]oxazin-3-one 
• 105807-80-5 6-amino-2-methyl-4H-benzo[1,4]oxazin-3-one 

Relevant academic research and scientific papers

MK2 INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

[Omim][BF4], a green and recyclable ionic liquid medium for the one-pot chemoselective synthesis of benzoxazinones

An efficient procedure for the one-pot chemoselective synthesis of 2H-benzo[b][1,4]oxazin-3(4H)-one derivatives from their corresponding o-aminophenols is developed using DBU in the ionic liquid [omim][BF4]. Upon completion of the reaction and separation of the product, the ionic liquid is recovered and successfully reused over nine recycles without any noticeable loss of performance.

Potent, orally bioavailable, liver-selective stearoyl-CoA desaturase (SCD) inhibitors

Two structurally distinct series of SCD (Δ9 desaturase) inhibitors (1 and 2) have been previously reported by our group. In the present work, we merged the structural features of the two series. This led to the discovery of compound 5b (CVT-12,012) which

HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE

The blow-described formula (I): [Ch. 1] a compound represented by formula (I) : (wherein k, m, n, and p each represent 0 to 2; j and q represents 0 or 1; R1 represents a halogen atom, a hydrocarbon group, a heterocyclic group, an alkoxy group,

Microwave-assisted one-pot regioselective synthesis of 2-alkyl-3,4-dihydro- 3-oxo-2H-1,4-benzoxazines

A protocol for regioselective one-pot synthesis of 2-alkyl-3,4-dihydro-3- oxo-2H-1,4-benzoxazines under controlled microwave heating has been developed. Starting from commercially available 2-aminophenols, a base-mediated regioselective O-alkylation took

Synthesis and pharmacological activity of 4 substituted 2,3 dihydro 1,4 benzoxazin 3 ones

Some derivatives of 3 oxo 2,3 dihydro 1,4 benzoxazine substituted with aminoalkyl and hydroxyalkyl groups were prepared and their analgesic activity studied. This was weak for the amino, but very important for the propranediol derivatives. One of them, AN