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Ethanone, 1-(5-amino-2-hydroxyphenyl)-, hydrochloride is a chemical compound that features a ketone group connected to a phenyl ring, which is further adorned with an amino and hydroxy group. Ethanone, 1-(5-amino-2-hydroxyphenyl)-, hydrochloride is widely recognized for its utility as a pharmaceutical intermediate, facilitating the synthesis of a broad spectrum of drugs and medications. The hydrochloride salt form of Ethanone, 1-(5-amino-2-hydroxyphenyl)-, hydrochloride not only bolsters its stability but also enhances its solubility in water, a property that is advantageous for the formulation of aqueous solutions. As a key building block in the realm of organic chemistry, Ethanone, 1-(5-amino-2-hydroxyphenyl)-, hydrochloride is instrumental in the innovation of novel therapeutic agents and the advancement of pharmaceutical products.

57471-32-6

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57471-32-6 Usage

Uses

Used in Pharmaceutical Industry:
Ethanone, 1-(5-amino-2-hydroxyphenyl)-, hydrochloride is utilized as a pharmaceutical intermediate for the synthesis of various drugs and medications. Its role in this capacity is pivotal, as it serves as a fundamental component in the creation of new therapeutic agents, contributing to the development of innovative treatments and medications.
Used in Organic Chemistry Research:
In the field of organic chemistry, Ethanone, 1-(5-amino-2-hydroxyphenyl)-, hydrochloride is employed as a versatile building block. Its structural features make it an attractive candidate for the exploration of new chemical reactions and the synthesis of complex molecules, thereby expanding the horizons of chemical research and discovery.

Check Digit Verification of cas no

The CAS Registry Mumber 57471-32-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,4,7 and 1 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 57471-32:
(7*5)+(6*7)+(5*4)+(4*7)+(3*1)+(2*3)+(1*2)=136
136 % 10 = 6
So 57471-32-6 is a valid CAS Registry Number.

57471-32-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(5-amino-2-hydroxyphenyl)ethanone,hydrochloride

1.2 Other means of identification

Product number -
Other names 5-amino-2-hydroxyacetophenone HCl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:57471-32-6 SDS

57471-32-6Relevant academic research and scientific papers

Spirocycles

-

, (2008/06/13)

Spirocycles of the general structural formulae: STR1 wherein: X is O, CH2 or SOm ; R1 is AlkylSO2 NH--, AlkylO--, AlkylSO2 --, AlkylCONH--, or NO2 --; R2 is --H, --OAlkyl, or --Alkyl; R3 is --NHCOCH2 SOm Phenyl, --NHCOCH2 SOm Alkyl, --NHCOC(CH3)2 OH, or NHSO2 Alkyl; R4 and R5 are --H, or --Alkyl; R6 is STR2 R7 is --H, --CN, --NHSO2 Alkyl, --Br, --OAlkyl, --NH2, --NO2, --NHCOAlkyl, or NHCONHAlkyl; R8 is --H, --OH, --CN, --OAlkyl, --CONHAlkyl, --NHSO2 Alkyl, --NHCOAlkyl, --SOm Alkyl, or --CO2 Alkyl; and m is 0-2; or a pharmaceutically acceptable salt, hydrate or crystal form thereof; which are Class III antiarrhythmic agents.

Asymmetric Synthesis of MK-0499

Tschaen, David M.,Abramson, Lee,Cai, Dongwei,Desmond, Richard,Dolling, Ulf-H.,et al.

, p. 4324 - 4330 (2007/10/02)

Described herein is an efficient asymmetric synthesis of the potent antiarrhthymia agent MK-0499.The route is convergent and is highlighted by two stereoselective reactions.A ruthenium-catalyzed, enantioselective hydrogenation of an enamide was developed for the preparation of the key amine intermediate.Oxazaborolidine-mediated ketone reduction was utilized to establish the alcohol stereochemistry.Optimization of this chemistry led to an IPA modified reduction method which provides enhanced stereoselectivity.

NITROGEN-CONTAINING SPIROCYCLES

-

, (2008/06/13)

Spirocycles of general structural formula: STR1 are Class III antiarrhythmic agents.

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