57497-07-1Relevant academic research and scientific papers
Carbonylation of cis-disubstituted epoxides to trans-β-lactones: Catalysts displaying steric and contrasteric regioselectivity
Mulzer, Michael,Coates, Geoffrey W.
, p. 11851 - 11862 (2014)
trans-β-Lactones are a versatile and useful class of compounds, but reliable methods for their direct synthesis are still limited. Addressing this problem, we present herein two catalysts for the regioselective carbonylation of cis-disubstituted epoxides. The two catalysts show high activities and opposing regioselectivities so that either one of the two possible β-lactone regioisomers can be obtained selectively.
