57497-18-4Relevant academic research and scientific papers
Carbocycle Formation via Intramolecular Insertion of Alkynes into Titanium-Carbon Bonds
Harms, Arthur E.,Stille, John R.
, p. 6565 - 6568 (2007/10/02)
Treatment of alkyl titanocene chloride complexes with the Lewis acids EtAlCl2 or Me2AlCl resulted in intramolecular insertion of a tethered alkyne into the Ti-C bond.Regioselective alkyne insertion produced exocyclic trisubstituted alkene products resulting from four-, five-, and six-membered ring formation.In the case of cyclohexane formation, the alkyne was found to insert with syn stereoselectivity.
