Ro 4-5509, also known as 4-(4-fluorophenyl)-1-(2-hydroxyethyl)-N-(4-methyl-1-piperazinyl)-1H-pyrazole-3-carboxamide, is a potent and selective antagonist of the α5 subunit-containing GABAA receptors. It is a synthetic compound that has been extensively studied for its potential therapeutic applications in various central nervous system disorders, such as anxiety, depression, and cognitive impairments. Ro 4-5509 works by binding to the α5 subunit of the GABAA receptor, which is involved in the regulation of neuronal excitability and synaptic plasticity. This selective antagonism can lead to enhanced cognitive function and reduced anxiety-like behavior in preclinical models. However, further research is needed to fully understand its potential clinical applications and safety profile.
The CAS Registry Mumber 5750-75-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,7,5 and 0 respectively; the second part has 2 digits, 7 and 5 respectively. Calculate Digit Verification of CAS Registry Number 5750-75: (6*5)+(5*7)+(4*5)+(3*0)+(2*7)+(1*5)=104 104 % 10 = 4 So 5750-75-4 is a valid CAS Registry Number.
5750-75-4Upstream product
5750-75-4Downstream Products
5750-75-4Relevant academic research and scientific papers