57507-94-5Relevant academic research and scientific papers
Efficient Green Synthesis and Computational Chemical Study of Some Interesting Heterocyclic Derivatives as Insecticidal Agents
Fahmy,Rizk,Hemdan,El-Sayed,Hassaballah
, p. 2545 - 2555 (2018)
A series of 5,5-diarylhydantoin (Dilantin) 3, 4, and 7, imidazole 1, 2, 5, 6, 8, and 9, thiazole 10–12, triazinthione 13, 15, 16, and 17, and thiadiazine 14 derivatives, containing diverse hydrophobic groups, were green synthesized through one-pot stepwise reaction of aromatic aldehydes, vitamin B1, and nitrogen nucleophiles, for example, urea, thiourea, and thiosemicarbazide using grinding technique as well as conventional thermal methods. Such synthesized compounds have potent insecticidal activities; for example, compounds 4, 6, and 17 exhibited the highest insecticidal activity against both Plutella xylostella and Helicoverpa armigera with minimum inhibitory concentration values at 500?μg/mL and LD50 activities at 50?μg/mL. The density functional theory was then applied to explore the structural and electronic characteristics of these compounds. All the synthesized compounds have been characterized based on their elemental analyses and spectral data.
An eco-friendly method for synthesis of symmetrical and unsymmetrical benzoin derivatives
Safari, Javad,Arani, Naimeh Moshtael,Isfahani, Anousheh Ramezan
experimental part, p. 495 - 498 (2011/12/21)
A rapid, highly efficient and mild green synthesis of symmetrical and unsymmetrical benzoin derivatives was achieved from the reaction of benzaldehyde derivatives with potassium cyanide in dimethyl sulfoxide under argon gas and ultrasound. This simple method affords benzoin derivatives at room temperature in short reaction times with high yield and purity.
