57508-73-3

Upstream product

• 5411-12-1 chalcone epoxide 
• 94-41-7 benzalacetophenone 
• 67295-26-5 2-hydroxy-3-(morpholin-4-yl)-1,3-diphenylpropan-1-one 

Downstream Products

• 130188-09-9 1-Acetyl-4-hydroxy-3,5-diphenyl-2-pyrazoline 
• 17953-06-9 4-Hydroxy-3,5-diphenyl-1H-pyrazole 
• 1145-01-3 3,5-Diphenylpyrazole 
• 130188-10-2 4-acetoxy-1-acetyl-3,5-diphenyl-4,5-dihydro-1H-pyrazole 
• 35228-98-9 3,5-diphenyl-1H-pyrazol-4-yl acetate 
• 130188-16-8 3,4,5-Trimethoxy-benzoic acid 1-acetyl-3,5-diphenyl-4,5-dihydro-1H-pyrazol-4-yl ester 
• 130188-12-4 Diphenyl-acetic acid 1-acetyl-3,5-diphenyl-4,5-dihydro-1H-pyrazol-4-yl ester 
• 130188-14-6 (E)-3-Phenyl-acrylic acid 1-acetyl-3,5-diphenyl-4,5-dihydro-1H-pyrazol-4-yl ester 
• 130188-15-7 Benzoic acid 1-acetyl-3,5-diphenyl-4,5-dihydro-1H-pyrazol-4-yl ester 
• 130188-13-5 Cyclopropanecarboxylic acid 1-acetyl-3,5-diphenyl-4,5-dihydro-1H-pyrazol-4-yl ester 
• 130188-21-5 Carbonic acid 3,5-diphenyl-1H-pyrazol-4-yl ester phenyl ester 
• 130188-11-3 Isobutyric acid 1-acetyl-3,5-diphenyl-4,5-dihydro-1H-pyrazol-4-yl ester 
• 130188-19-1 4-Fluoro-benzoic acid 3,5-diphenyl-1H-pyrazol-4-yl ester 
• 130188-17-9 Phenyl-acetic acid 3,5-diphenyl-1H-pyrazol-4-yl ester 

Relevant academic research and scientific papers

Synthesis of N-containing heterocycles via mechanochemical grinding and conventional techniques

Mechano heterocyclic chemistry is a recent quickly growing technique draws the attention of hetrocyclic chemists towards the use of grindstone technique in a solvent free green efficient clean synthesis of many heterocyclic systems. α,β-Epoxy ketones were used as a unique scaffold for synthesis of stable hydroxyazoles. The key advantage of grinding technique over the conventional thermal technique includes its simple, solvent free conditions, as well as facile work up with high yield economy. It is also successful in achieving three of the green chemistry objectives of a solvent free, high atom economy, save energy thus combining the features of both economic and environmental advantages.

Mannich bases as synthetic intermediates: Synthesis of 3- and 4-functionalized 2-pyrazolines

The reaction of styryl ketonic Mannich bases 2a - c with phenylhydrazine leads to 3-functionalized 2-pyrazolines 4 or 6 depending on the reaction conditions. 3-[β-(Arylamino)ethyl]-2-pyrazolines 8a,b were obtained via transamination between the methiodide

Synthesis of 3,5-diphenyl-1H-pyrazoles

An efficient and convenient synthesis of 3,5-diphenyl-1N-pyrazoles from chalcones by the action of hydrazine hydrate on chalcone-epoxide followed by simultaneous dehydration is reported. Copyright Taylor & Francis, Inc.