57521-18-3Relevant academic research and scientific papers
Convenient synthesis of heterocyclic compounds with dihydropyrano[3,4-b] pyridine scaffold
Pacquelet, Sandrine,Blache, Yves,Kimny, Tan,Dubois, Marie-Aleth Lacaille,Desbois, Nicolas
, p. 1092 - 1100 (2013)
A general method for the preparation of various substituted dihydropyrano [3,4-b]pyridines is reported. The formation of pyranopyridine structure was achieved by a Polonovski rearrangement of pyridine N-oxide with acetic anhydride, giving 2-(acetoxymethyl)-pyridine followed by an hydrolyzed and an intramolecular Williamson ether formation.
An efficient route to a 5,6-dihydropyrano[3,4-b]pyridin-8-one core in two steps from enaminolactones
Sall, Cheikh,Desbois, Nicolas,Paquelet, Sandrine,Camacho, José R.,Chezal, Jean Michel,Teulade, Jean-Claude,Blache, Yves
, p. 1301 - 1304 (2008/09/18)
A convenient two step conversion of heterocyclic enaminolactones to heterocyclic fused 2-pyran-1-ones is reported. The use of this method can be applied to a wide variety of aromatic and heteroaromatic amines to give potentially biologically active compounds in good yields.
TOPICAL FORMULATIONS
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Page/Page column 89, (2008/12/05)
There is provided topical pharmaceutical compositions comprising compounds of formula (I) wherein R1, R2, R3 and X have meanings given in the description. These compositions can be used to treat microbial infections and to
USE OF PYRROLOQUINOLINE COMPOUNDS TO KILL CLINICALLY LATENT MICROORGANISMS
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Page/Page column 87, (2008/06/13)
There is provided the use of compounds of formula (I), wherein R1 R2 R3 and X have meanings given in the description, for the preparation of a medicament for killing clinically latent microorganisms. There is also provided
