57523-13-4Relevant articles and documents
SUBSTITUTED IMIDAZOLECARBOXYLATE DERIVATIVES AND THE USE THEREOF
-
Paragraph 0532-0534, (2020/12/08)
A compound is shown in formula (I). The derivatives of the compound include a stereoisomer, a pharmaceutically acceptable salt, a solvate, a prodrug, a metabolite, a deuterated derivative. The compound is a structurally novel substituted imidazole formate derivative. Substituted imidazole formate derivatives are used in preparing a drug with sedative, hypnotic and/or anesthetic effects, as well as a drug that can control the state of epilepsy. The compound has a good inhibitory effect on the central nervous system, and provides a new option for clinical screening of and/or preparation of a drug with sedative, hypnotic and/or anesthetic effects and controlling the state of epilepsy.
Study of Effects on the Coordination of Thioether Ligands, 2. Stereospecific Ligand Substitutions in Manganese (I) Complexes
Tsai, Shiou-chuan,Wang, Hsin-Ell,Huang, Chi-Tsuan,Yiin, Lih-Ming,Liu, Shiuh-Tzung
, p. 151 - 156 (2007/10/02)
Treatment of fac- and fac- with silver hexafluorophosphate yields the η3-tripodal manganese complexes PF6 (7) and PF6 (9), respectively, whereas the reaction of CH3C(CH2PPh2)2(CH2SH) with Mn(CO)5Br gives directly Mn(CO)3 (11).Both ionic complexes 7 and 9 undergo stereospecifically ligand substitution upon treatment with Br(-), I(-), N3(-), SCN(-) and CN(-) to give syn-fac- and syn-fac- (X = Br, I, SCN, N3, CN) respectively, but the neutral complex 11 fails to undergo such a substitution reaction with these ions.However, reaction of I(-) with the complex Mn(CO)3>BF4 (20) , which is obtained from the S-alkylation of 11 with the (CH3)3OBF4, affords syn-fac-Mn(CO)3I (22s) exclusively.The possible reaction mechanism of this ligand substitution is discusssed. - Key Words: Tripodal ligands/ Phosphane ligands/ Thioethers/ Manganese complexes