5753-26-4

Usage

Uses

Used in Pharmaceutical Synthesis:
1-(2-Chloro-ethyl)-4-methyl-piperazin is used as a key intermediate in the synthesis of pharmaceutical compounds. Its unique chemical structure allows for the development of new drugs with potential therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, 1-(2-CHLORO-ETHYL)-4-METHYL-PIPERAZINE serves as an important intermediate, facilitating the creation of various organic compounds for research and industrial purposes.
Used in Chemical Research:
1-(2-Chloro-ethyl)-4-methyl-piperazin is utilized in chemical research to explore its reactivity and potential applications in the development of new chemical entities and processes. Its unique properties make it a valuable tool for understanding and advancing chemical reactions and mechanisms.

Upstream product

• 109-01-3 1-methyl-piperazine 
• 107-04-0 1-Bromo-2-chloroethane 
• 40676-05-9 2-(4-methyl-piperazino)-ethanol; dihydrochloride 

Downstream Products

• 102321-83-5 1-(2-diphenylamino-ethyl)-4-methyl-piperazine 

Relevant academic research and scientific papers

INDENOISOQUINOLINONE DERIVATIVES, MANUFACTURING METHOD AND MEDICAL USE THEREOF

Indenoisoquinolinone derivatives (I), the manufacturing method and the medical use thereof, which belong to pharmaceutical chemistry and organic chemistry field, are disclosed. These compounds can be used for treating several medical symptoms related to postmenopausal syndrome, uterine fibers deterioration and aortic smooth muscle cells proliferation, especially ER-(+) depend breast cancer. Meanwhile, these compounds can also be used for treating glioma and lung cancer, and have inhibiting effect on tumor metastasis effect on tumor metastasis.

Indole nitriles

Compounds of the formula (I) wherein m, n, R1, R2, R3, R4, R5 and R6 are as described herein, together with methods for making the compounds and using the compounds for treatment of diseases or conditions mediated by Cathepsin K.

Cationic polysaccharides and reagents for their preparation

Cationic polysaccharide derivatives are prepared by reacting a polysaccharide with a polycationic reagent having one polysaccharide reactive group and at least two cationic groups. Suitable reagents include polycationic alkyl, aryl, alkaryl, cycloaliphatic, or heterocyclic amines, some of which are novel compositions. The polycationic polysaccharide derivatives prepared from these reagents are useful in the manufacture of paper.

Isoindolone derivatives, their preparation and the pharmaceutical compositions containing them

This invention relates to isoindolone derivatives of general formula (I) in which the radicals R are hydrogen atoms or together form a bond, the symbols R'' are phenyl radicals which can be substituted by a halogen atom or a methyl radical in position 2 or 3, X is an oxygen or sulphur atom or a radical N--R 3, R 3 being H, optionally substituted alkyl or dialkylamino, R 1 is optionally substituted phenyl or cyclohexadienyl, naphthyl or a heterocycle and R 2 is H, halogen, OH, alkyl, amionoalkyl, alkylaminoalkyl, dialkylaminoalkyl, alkoxy, alkylthio, acyloxy, carboxyl, optionally substituted alkoxycarbonyl, benzyloxycarbonyl, amino or acylamino, in their (3aR,7aR) forms or in the (3aRS,7aRS) form or their mixtures, and if appropriate their salts where such exist, and their preparation.The new derivatives according to the invention are particularly valuable as antagonists of substance P. STR1