57536-38-6Relevant academic research and scientific papers
Ruthenium(II)-Catalyzed ortho-C-H Chalcogenation of Benzoic Acids via Weak O-Coordination: Synthesis of Chalcogenoxanthones
Mandal, Anup,Dana, Suman,Sahoo, Harekrishna,Grandhi, Gowri Sankar,Baidya, Mahiuddin
supporting information, p. 2430 - 2433 (2017/05/12)
A general protocol for direct chalcogenation of inert C-H bonds of (hetero)aromatic carboxylic acids is developed with a ruthenium(II) catalyst using readily available starting materials, offering densely substituted ortho-chalcogenyl aromatic acids in high yields (up to 96%). The strategy avoids the installation of an external directing group, use of metallic oxidants, and features operational simplicity with ample substrate scope. Synthetic application en route to biologically important chalcogenoxanthones is also demonstrated. This work represents the first example of ruthenium(II)-catalyzed direct C-H chalcogenation of benzoic acids.
Regioselective copper-catalyzed C-N and C-S bond formation using amines, thiols and halobenzoic acids
Liu, Shuanglong,Pestano, John Paul C.,Wolf, Christian
, p. 3519 - 3527 (2008/09/19)
A regioselective method for highly efficient C-N and C-S bond formation with 2-halobenzoic acids is described. The Cu/Cu2O-catalyzed reaction is carried out in 2-ethoxyethanol or ethylene glycol diethyl ether and does not require the use of strong base or other additives. This procedure eliminates the need for acid protection, tolerates a wide range of functional groups and provides aromatic and aliphatic amines and sulfides in 81-99% yield. Georg Thieme Verlag Stuttgart.
