57547-92-9 Usage
Uses
Used in Pharmaceutical Synthesis:
1-(propylsulfonyl)pyrrolidine is used as a key intermediate for the synthesis of pharmaceuticals. Its unique structure allows it to be a valuable building block in the development of new drugs, contributing to the creation of a wide range of medicinal compounds.
Used in Agrochemical Production:
In the agrochemical industry, 1-(propylsulfonyl)pyrrolidine is utilized as a component in the synthesis of various agrochemicals. Its incorporation aids in the development of effective products for agricultural applications, enhancing crop protection and yield.
Used as a Building Block in Organic Chemistry:
1-(propylsulfonyl)pyrrolidine serves as a fundamental building block in organic chemistry. It is employed for the creation of diverse functional groups and chemical structures, which are essential in the synthesis of complex organic molecules.
Used as a Chiral Auxiliary in Asymmetric Synthesis:
1-(propylsulfonyl)pyrrolidine has demonstrated its potential as a chiral auxiliary in asymmetric synthesis. It plays a crucial role in enhancing the selectivity and yield of enantioselective reactions, which is vital for producing optically active compounds with specific biological activities.
Used in Biological Activity and Pharmacological Research:
1-(propylsulfonyl)pyrrolidine has shown promise in biological activity studies and is being investigated for its potential pharmacological applications. This research could lead to the discovery of new therapeutic agents and contribute to advancements in medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 57547-92-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,5,4 and 7 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 57547-92:
(7*5)+(6*7)+(5*5)+(4*4)+(3*7)+(2*9)+(1*2)=159
159 % 10 = 9
So 57547-92-9 is a valid CAS Registry Number.
57547-92-9Relevant academic research and scientific papers
One-pot synthesis of sulfonamides from methyl sulfinates using ultrasound
García Ruano, José L.,Parra, Alejandro,Marzo, Leyre,Yuste, Francisco,Mastranzo, Virginia M.
experimental part, p. 2905 - 2910 (2011/05/05)
Room temperature ultrasonic irradiation of neat mixtures of methyl sulfinates and primary or secondary amines (1.5 equiv) produced sulfinamides, which on m-CPBA oxidation (in dichloromethane) were converted into the corresponding sulfonamides. The two steps can be accomplished in one pot, in good overall yields, when using secondary amines, but primary amines give better sulfonamide yields when the peracid oxidation is effected on the purified sulfinamide. This constitutes a mild, efficient, and potentially scalable route to sulfonamides, which obviates the use of water sensitive, often lachrymatory sulfonyl chlorides and large reagent excesses.
Mild and general method for the synthesis of sulfonamides
Garcia Ruano, Jose Luis,Parra, Alejandro,Yuste, Francisco,Mastranzo, Virginia M.
, p. 311 - 319 (2008/12/22)
Reaction of methyl sulfinates with lithium amides followed by 3-chloroperoxybenzoic acid oxidation of the resulting sulfinamides provides primary, secondary, and tertiary alkane-, arene-and heteroarenesulfonamides in high yields. This constitutes a mild and facile experimental protocol that avoids the use of hazardous, unstable, or volatile reagents and does not affect the configurational stability of the amines. Georg Thieme Verlag Stuttgart.
