575474-35-0

Upstream product

• 90923-04-9 methyl 2-(2-methyl-5-nitrophenoxy)acetate 
• 5428-54-6 2-methyl-5-nitrophenol 
• 575474-36-1 N-methyl-2-(2-methyl-5-nitrophenoxy)acetamide 

Relevant academic research and scientific papers

2,4-Pyrimidinediamine Compounds and Their Uses

The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators via degranulation and other processes effected by activation of the IgE and/or IgG receptor signaling cascades.

COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY

The invention encompasses compounds having formula (I-V) and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK3, may be therapeutically useful.