Basic information

Product Name: R 112 (pharMaceutical)
Synonyms: R 112 (pharMaceutical);Phenol, 3,3'-[(5-fluoro-2,4-pyrimidinediyl)diimino]bis-
CAS NO:575474-82-7
Molecular Formula: C16H13FN4O2
Molecular Weight: 312.2984232
EINECS: N/A
Product Categories: N/A
Mol File: 575474-82-7.mol

Chemical Properties

Melting Point: N/A
Boiling Point: 552.0±60.0 °C(Predicted)
Flash Point: N/A
Appearance: /
Density: 1.494±0.06 g/cm3(Predicted)
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
PKA: 9.48±0.10(Predicted)
CAS DataBase Reference: R 112 (pharMaceutical)(CAS DataBase Reference)
NIST Chemistry Reference: R 112 (pharMaceutical)(575474-82-7)
EPA Substance Registry System: R 112 (pharMaceutical)(575474-82-7)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 575474-82-7(Hazardous Substances Data)

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Usage
SDS
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575474-82-7 Usage

Uses

Used in Biological Studies:
R 112 (pharMaceutical) is used as a Syk inhibitor for the study and therapeutic application of cultured human mast cells (CHMC). It aids in the design and structure-activity relationship of IgE-mediated mast cell activation inhibitors, which are crucial for understanding the underlying mechanisms of mast cell activation and the development of potential treatments for related conditions.
Used in Pharmaceutical Industry:
R 112 (pharMaceutical) is used as a Syk inhibitor for the development of therapeutic agents targeting mast cell and basophil degranulation. Its ability to inhibit these processes makes it a promising candidate for the treatment of conditions involving mast cell activation, such as allergies, asthma, and autoimmune diseases. Furthermore, its inhibitory effects on leukotriene C4 production and cytokine levels in cultured human mast cells suggest its potential in modulating immune responses and inflammation.

Check Digit Verification of cas no

The CAS Registry Mumber 575474-82-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,7,5,4,7 and 4 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 575474-82:
(8*5)+(7*7)+(6*5)+(5*4)+(4*7)+(3*4)+(2*8)+(1*2)=197
197 % 10 = 7
So 575474-82-7 is a valid CAS Registry Number.

575474-82-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	3,3'-[(5-Fluoro-2,4-pyrimidinediyl)diimino]diphenol

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:575474-82-7 SDS

575474-82-7Upstream product

575474-82-7Downstream Products

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