57567-95-0

Usage

Uses

Used in Sunscreen Industry:
4-(5-Chloro-2H-benzotriazol-2yl)-1,3-Benzenediol is used as a UV filter for its ability to absorb or reflect harmful UV radiation from the sun. This helps protect the skin from sun damage and reduces the risk of skin cancer.
Used in Skincare Products:
4-(5-Chloro-2H-benzotriazol-2yl)-1,3-Benzenediol is used as an ingredient in various skincare products for its antioxidant properties. The presence of hydroxy groups in the benzenediol moiety provides additional protective effects on the skin, promoting skin health.

Upstream product

• 114462-02-1 5-Chloro-2-(2,4-dimethoxy-phenyl)-2H-benzotriazole 
• 89284-65-1 4-chloro-2-nitro-1-nitrosobenzene 
• 2735-04-8 2,4-Dimethoxyaniline 
• 114461-95-9 4-chloro-2',4'-dimethoxy-2-nitroazobenzene 

Relevant academic research and scientific papers

Process for the preparation of benzotriazole derivatives

2-(2'-Hydroxyphenyl)-2H-benzotriazoles of formula (I): STR1 wherein: R1, R2, R3, R4, R5, R6, R7, R8 and Z are defined in the specification, are prepared by catalytic hydrogenation of a suitable o-nitroazo dye compound in the presence of a PtS, Pt, Pd, Pt/Pd or other noble metal hydrogenation catalyst, in the presence of a base, an acid and a hydroxylic solvent.

Preparation of Some 2-(Methoxyphenyl)-2H-benzotriazoles and the Corresponding Hydroxyphenyl Compounds

The reaction of several substituted o-nitronitrosobenzenes with o- and p-anisidine, and 2,4-dimethoxyaniline in acetic acid gives in good yield the corresponding o-nitroazobenzenes which are readily reduced with thiourea dioxide (formamidinesulfinic acid) to the corresponding 2-(methoxyphenyl)-2H-benzotriazoles, demethylation of which furnished the corresponding 2-(hydroxyphenyl)-2H-benzotriazoles.Demethylation of the dimethoxy derivatives was best accomplished with boron tribromide in methylene chloride, the methoxy group located ortho to the benzotriazole ring beingdemethylated more readily than is the para-methoxy group.The reaction of 0-nitroazobenzenes containing a methoxy group with hydrobromic acid in acetic acid results in cleavage of the azo bond and also partial bromination to give o-nitroaniline and some of its brominated derivatives.