57616-69-0 Usage
Uses
Used in Organic Synthesis:
1-(3-CHLOROPROPYL)-PYRROLIDINE HYDROCHLORIDE is used as a chiral auxiliary reagent for its ability to influence the stereochemistry of chemical reactions, which is crucial in the synthesis of enantiomerically pure compounds.
Used in Pharmaceutical Production:
1-(3-CHLOROPROPYL)-PYRROLIDINE HYDROCHLORIDE is used as a key intermediate in the manufacturing process of certain antihistamine and antiemetic medications, contributing to the development of drugs that address allergic reactions and nausea.
Used in Agrochemicals:
1-(3-CHLOROPROPYL)-PYRROLIDINE HYDROCHLORIDE is also utilized in the production of various agrochemicals, where its chiral properties are essential for the synthesis of biologically active compounds that can be used in agriculture for pest control and crop protection.
Used in Research Chemicals:
Due to its versatility and reactivity, 1-(3-CHLOROPROPYL)-PYRROLIDINE HYDROCHLORIDE is employed in the synthesis of research chemicals, facilitating the exploration of new chemical entities and potential therapeutic agents in scientific studies.
Check Digit Verification of cas no
The CAS Registry Mumber 57616-69-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,6,1 and 6 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 57616-69:
(7*5)+(6*7)+(5*6)+(4*1)+(3*6)+(2*6)+(1*9)=150
150 % 10 = 0
So 57616-69-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H14ClN.ClH/c8-4-3-7-9-5-1-2-6-9;/h1-7H2;1H
57616-69-0Relevant academic research and scientific papers
CHEMICAL PROCESS
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Page/Page column 49-50, (2008/12/05)
The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-fluoro-2-methylindol-5-yloxy)-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline.
New mustard-linked 2-aryl-bis-benzimidazoles with anti-proliferative activity
Le Sann, Christine,Baron, Anne,Mann, John,Van Den Berg, Hendrik,Gunaratnam, Mekala,Neidle, Stephen
, p. 1305 - 1312 (2007/10/03)
We describe new methodology for the synthesis of symmetric bis-benzimidazoles carrying 2-aryl moieties, including 2-[4-(3′- aminopropoxy)phenyl] and 2-[4-(3′-aminopropanamido)phenyl] substituents, together with the synthesis of novel hybrid molecules comprising bis-benzimidazoles in ester and amide combination with the N-mustard chlorambucil. The in vitro activities of these compounds against five cancer cell lines are also provided. The Royal Society of Chemistry 2006.
