5763-53-1

Basic information

• Product Name: CYCLOPENTANE-1,1-DIYLDIMETHANOL
• Synonyms: CYCLOPENTANE-1,1-DIYLDIMETHANOL;1,1-Bis(hydroxymethyl)cyclopentane;1,1-Cyclopentanedimethanol;(1-methylolcyclopentyl)methanol;[1-(hydroxymethyl)cyclopentyl]methanol;NSC 49657
• CAS NO: 5763-53-1
• Molecular Formula: C₇H₁₄O₂
• Molecular Weight: 130.18486
• Mol File: 5763-53-1.mol

Chemical Properties

• Boiling Point: 257.7 °C at 760 mmHg
• Flash Point: 124.4 °C
• Appearance: /
• Density: 1.047 g/cm³
• Vapor Pressure: 0.00213mmHg at 25°C
• Refractive Index: 1.481
• CAS DataBase Reference: CYCLOPENTANE-1,1-DIYLDIMETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: CYCLOPENTANE-1,1-DIYLDIMETHANOL(5763-53-1)
• EPA Substance Registry System: CYCLOPENTANE-1,1-DIYLDIMETHANOL(5763-53-1)

Safety Data

• Hazardous Substances Data: 5763-53-1(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
CYCLOPENTANE-1,1-DIYLDIMETHANOL is used as a key intermediate in the synthesis of various chemical compounds for [application reason] its ability to react with a wide range of other chemicals to form new products.
Used in Solvent Applications:
In the Chemical Industry, CYCLOPENTANE-1,1-DIYLDIMETHANOL is used as a solvent for [application reason] its capacity to dissolve a variety of substances, facilitating various chemical reactions and processes.
Used in Polymer Production:
CYCLOPENTANE-1,1-DIYLDIMETHANOL is used as a monomer or a reactant in the production of polyesters and polyurethanes for [application reason] its ability to polymerize and form long-chain molecules that are useful in creating plastics and other materials.
Used in Pharmaceutical Synthesis:
In the Pharmaceutical Industry, CYCLOPENTANE-1,1-DIYLDIMETHANOL is used as a building block in the synthesis of various drugs for [application reason] its chemical properties that allow it to be incorporated into the molecular structures of medicinal compounds.
Used in Agrochemical Production:
CYCLOPENTANE-1,1-DIYLDIMETHANOL is used as a component in the formulation of agrochemicals for [application reason] its role in creating effective and stable active ingredients for agricultural applications.

InChI:InChI=1/C7H14O2/c8-5-7(6-9)3-1-2-4-7/h8-9H,1-6H2

Upstream product

• 50-00-0 formaldehyd 
• 872-53-7 cyclopentanealdehyde 
• 1449746-43-3 (cyclopentane-1,1-diylbis(methylene))bis(oxy)bis(tert-butyldiphenylsilane) 
• 1449746-42-2 (cyclopentane-1,1-diylbis(methylene))bis(oxy)bis(triisopropylsilane) 
• 1449746-41-1 (cyclopentane-1,1-diylbis(methylene))bis(oxy)bis(tert-butyldimethylsilane) 
• 4167-77-5 cyclopentane-1,1-dicarboxylic acid diethyl ester 

Downstream Products

• 68499-28-5 1,1-bis-(bromomethyl)-cyclopentane 
• 102539-92-4 1-hydroxymethyl-cyclopentanecarboxylic acid 
• 956519-89-4 1-(tert-butyldiphenylsilanyloxymethyl)cyclopentanecarbaldehyde 
• 956521-03-2 [1-(tert-butyldiphenylsilanyloxymethyl)cyclopentyl]methanol 
• 941687-71-4 1-benzyloxymethyl-cyclopentanecarbaldehyde 
• 3187-32-4 2,2'-(cyclopentane-1,1-diyl)bis(ethan-1-ol) 
• 16713-66-9 1,1-cyclopentanediacetic acid 
• 1276693-12-9 [1-(tert-butyl-dimethyl-silanyloxymethyl)-cyclopentyl]-methanol 
• 738625-06-4 C₁₅H₂₂O₃ 

Relevant articles and documents

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with a defect in glyoxylate metabolism, for example a disease or disorder associated with the enzyme glycolate oxidase (GO) or alterations in oxalate metabolism. Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the enzyme glycolate oxidase (GO). Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.

Helianthus-like cucurbit[4]uril and cucurbit[5]uril analogues

A new glycoluril-like molecule, cyclopentanopropanediurea (CyP-TD), was prepared by malonic ester synthesis. Its condensation with paraformaldehyde resulted in two Helianthus-like cucurbituril analogues, CyP4TD[4] and CyP5TD[5], with cyclopentano groups evenly distributed on the equators. The structures of the two macrocycles were confirmed by 1H-NMR, HRMS-ES and single-crystal X-ray diffraction. CyP4TD[4] and CyP5TD[5] both exhibit excellent thermal stability, and CyP5TD[5] has better solubility in water and organic solvents, while CyP4TD[4] can hardly dissolve in them.

Aluminium chloride hexahydrate (AlCl3.6H2o): An efficient, facile, mild, and highly chemoselective catalytic deprotection of tert-butyldimethylsilyl (tbs) ethers

tert-Butyldimethylsilyl (TBS) phenyl / alkyl ethers were cleaved to the corresponding efficiently parent hydroxyl compounds in good yields using catalytic amounts of AlCl3.6H2O by conventional or microwave-assisted heating in methanol or isopropanol solution. Intramolecular and competitive experiments demonstrated the chemoselective deprotection of TBS ethers in the presence of triisopropylsilyl and tert-butyldiphenylsilyl ethers.

APOPTOSIS INDUCERS

This invention comprises novel compounds which inhibit the activity of anti-apoptotic Bcl-2 family protein members, compositions containing the compounds and methods of treating diseases involving a defect in apoptosis, such as, for example, in the treatment of cancer.

Cerium(IV) sulfate tetrahydrate: A catalytic and highly chemoselective deprotection of THP, MOM, and BOM ethers

Tetrahydropyranyl (THP), methoxymethyl (MOM), and benzyloxymethyl (BOM) phenyl/alkyl ethers were efficiently cleaved to the corresponding parent hydroxyl compounds in good yields using catalytic amounts of Ce(SO 4)2·4H2O by microwave-assisted or conventional heating in methanol solution. Intramolecular and competitive experiments demonstrated the chemoselective deprotection of THP ethers in the presence of triisopropylsilyl (TIPS) and tert-butyldiphenylsilyl (TBDPS) phenyl ethers.

Selective deprotection of TBDMS alkyl ethers in the presence of TIPS or TBDPS phenyl ethers by catalytic CuSO4·5H2O in methanol

TBDMS alkyl ethers are efficiently cleaved to the corresponding hydroxyl compounds upon heating (conventional or microwave) in methanol solution containing 20 mol % CuSO4·5H2O. Intramolecular chemoselective experiments showed that TBDMS alkyl ethers are selectively cleaved in the presence of TIPS or TBDPS aryl ethers. Competition experiments also showed that TBDMS alkyl ethers were selectively cleaved in the presence of TBDPS alkyl ethers.

Hydroxyl-containing monomer, polymer, resist composition, and patterning process

A hydroxyl-containing monomer of formula (1) is provided wherein R1 is H, F, methyl or trifluoromethyl, R2 and R3 are monovalent C1-C15 hydrocarbon groups, or R2 and R3 may form an aliphatic ring. The monomers are useful for the synthesis of polymers which have high transparency to radiation of up to 500 nm and the effect of controlling acid diffusion so that the polymers may be used as a base resin to formulate radiation-sensitive resist compositions having a high resolution.

Laser-Powered Decomposition of Spiroalkanes (n = 2-5)

The laser heating of spiroalkanes (n=2-5) and of their 1,1,2,2-tetradeuterated isotopomers reveals dissimilar modes of their thermal decomposition.Spiropentane decomposes into ethene and propadiene via two competing routes: the direct cleavage and the more important cleavage via intermediary methylenecyclobutane.Spirohexane decomposes through two important concurrent pathways which are the expulsions of ethene from the three-membered ring and a more feasible expulsion of ethene from the four-membered ring.Spiroheptane and spirooctane decompose by a radical-chain mechanism and afford complex mixtures of products; upon addition of propene both compounds rearrange into two cycloalkanes wherein the larger ring of the spiroalkane is preserved and substituted with ethylidene and a vinyl group.

Insecticidal ethers

Insecticidally active compounds of the formula (I): STR1 wherein R4 represents a group selected from those groups represented by R5 in insecticidally active compounds of formula: STR2 R3 is selected from fluoromethyl and difluoromethyl, and either (a) R1 and R2 represent alkyl of one, two, three or four carbon atoms, or (b) R1 and R2 taken together with the adjacent carbon atom form a cycloalkyl ring of four, five or six carbon atoms.