57642-05-4

Basic information

• Product Name: 1-(1H-Indol-3-Yl)-2-Iodo-Ethanone
• Synonyms: 1-(1H-Indol-3-Yl)-2-Iodo-Ethanone;1-(1H-Indol-3-Yl)-2-Iodo-Ethanone(WX630252)
• CAS NO: 57642-05-4
• Molecular Formula: C10H8INO
• Molecular Weight: 285.08109
• Mol File: 57642-05-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(1H-Indol-3-Yl)-2-Iodo-Ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1H-Indol-3-Yl)-2-Iodo-Ethanone(57642-05-4)
• EPA Substance Registry System: 1-(1H-Indol-3-Yl)-2-Iodo-Ethanone(57642-05-4)

Safety Data

• Hazardous Substances Data: 57642-05-4(Hazardous Substances Data)

Usage

General Description

1-(1H-Indol-3-Yl)-2-Iodo-Ethanone, also known as 3-indole-2-iodopropan-1-one, is a chemical compound with the molecular formula C10H8INO. It is a derivative of indole and contains a ketone and iodo group. 1-(1H-Indol-3-Yl)-2-Iodo-Ethanone is often used in organic synthesis and pharmaceutical research due to its potential biological activity. It has been studied for its potential as an anti-cancer agent and as a precursor for the synthesis of other pharmaceutical compounds. 1-(1H-Indol-3-Yl)-2-Iodo-Ethanone is a versatile compound with potential applications in various fields of chemistry and medicine.

Upstream product

• 703-80-0 3-acetylindole 

Downstream Products

• 73053-81-3 pimprinethine 

Relevant articles and documents

Mild and General Synthesis of Pyrrolo[2,1-a]isoquinolines and Related Polyheterocyclic Frameworks from Pyrrole Precursors Derived from a Mechanochemical Multicomponent Reaction

The combination of a three-component, solvent-free pyrrole synthesis performed under mechanochemical conditions with a TMSOTf-catalyzed oxonium-mediated cyclization gave general access to pyrrolo[2,1-a]isoquinoline derivatives under very mild conditions.

Logic design and synthesis of quinoxalines via the integration of iodination/oxidation/cyclization sequences from ketones and 1,2-diamines

A novel protocol for the synthesis of quinoxalines has been developed from simple ketones and 1,2-diamines. This process underwent a logic approach to bis-substituted quinoxalines via a consecutive iodination/Kornblum oxidation/cyclization in the presence of I2/CuO/DMSO and to mono-substituted quinoxalines via an iodination/cyclization/aromatization in the presence of I2/CuO/K3PO4·3H 2O.