57646-87-4 Usage
Uses
Used in Organic Synthesis:
DTAD is used as an esterification catalyst for facilitating the formation of esters from carboxylic acids and alcohols. Its reactivity and efficiency in catalyzing esterification reactions make it a valuable tool in organic synthesis processes.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, DTAD is utilized as an intermediate in the synthesis of various drugs. Its role in creating complex organic compounds that are precursors to active pharmaceutical ingredients highlights its importance in drug development.
Used in Agrochemical Production:
DTAD also finds application in the agrochemical sector, where it serves as an intermediate in the synthesis of pesticides and other agrochemical products. Its contribution to the development of effective and safe agrochemicals is significant.
Used in Environmentally Friendly Reagents:
Due to its biodegradability and low toxicity, DTAD is used as an environmentally friendly reagent in various chemical processes. This aspect of DTAD makes it a preferred choice for green chemistry applications, where reducing environmental impact is a priority.
Used in Compound Library Preparation:
DTAD is employed in the preparation of carboxylic acid-derived compound libraries, which are essential for high-throughput screening in drug discovery. Its ability to facilitate the synthesis of diverse compounds makes it instrumental in creating comprehensive libraries for research purposes.
Check Digit Verification of cas no
The CAS Registry Mumber 57646-87-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,6,4 and 6 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 57646-87:
(7*5)+(6*7)+(5*6)+(4*4)+(3*6)+(2*8)+(1*7)=164
164 % 10 = 4
So 57646-87-4 is a valid CAS Registry Number.
57646-87-4Relevant academic research and scientific papers
REACTION OF N,N-DICHLOROAMIDES WITH TRICHLOROETHYLENE
Mirskova, A. N.,Levkovskaya, G. G.,Gogoberidze, I. T.,Kalikhman, I. D.,Voronkov, M. G.
, p. 239 - 241 (2007/10/02)
The reaction of N,N-dichloroacetamide and N,N-dichlorobenzamide with trichloroethylene in an inert atmosphere leads to the formation of the products from the transformation of the corresponding acylimines of chloral, i.e. 2,2,2-trichloro-1,1-di(acetamido)benzamido ethanes, N-(2,2,2-trichloro-1-hydroxyethyl)acetamides and the corresponding benzamides, and pentachloroethane.In the reaction of N,N-dichlorobenzamide with trichloroethylene in the presence of atmospheric oxygen N-(dichloroacetyl)benzamide is obtained in additon to N-(2,2,2-trichloro-1-hydroxyethyl)benzamide and pentachloroethane.Its formation results from the parallel processes of oxidation of the trichloroethylene to dichloroacetyl chloride and reduction of the dichlorobenzamide to benzamide and their reaction.
