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3-amino-3-deoxy-D-glucose hydrochloride, also known as Cladinose, is a deoxy sugar derived from D-glucose. It is a monosaccharide with an amino group at the 3-position and a hydroxyl group at the 6-position. 3-amino-3-deoxy-D-glucose hydrochloride is commonly used in the pharmaceutical industry and has various applications due to its unique structure and properties.

57649-10-2

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57649-10-2 Usage

Uses

Used in Pharmaceutical Industry:
3-amino-3-deoxy-D-glucose hydrochloride is used as an intermediate for the synthesis of various antibiotics, particularly those belonging to the aminoglycoside class. Its role in the synthesis process is crucial for the development of these life-saving drugs.
Used in Antifungal Applications:
3-amino-3-deoxy-D-glucose hydrochloride is used as an antifungal agent for inhibiting the growth of various human pathogenic fungi, including Candida albicans. It works by disrupting the synthesis of fungal cell walls, thereby preventing their growth and spread.
Used in Antibacterial Applications:
In addition to its antifungal properties, 3-amino-3-deoxy-D-glucose hydrochloride also exhibits antibacterial activity against certain bacterial species, such as Staphylococcus aureus. It can be used as an alternative or supplement to conventional antibiotics, providing a valuable tool in the fight against bacterial infections.
Used in Crop Protection:
3-amino-3-deoxy-D-glucose hydrochloride has been explored as an alternative to synthetic pesticides and genetic resistance in crop plants for the management of plant diseases. It can inhibit cell wall synthesis in plant-pathogenic oomycetes, providing a natural and environmentally friendly approach to crop protection.

references

[1] milner j l, silo-suh l, lee j c, et al. production of kanosamine by bacillus cereus uw85[j]. applied and environmental microbiology, 1996, 62(8): 3061-3065.[2] dolak l a, castle t m, dietz a, et al. 3-amino-3-deoxyglucose produced by a streptomyces sp[j]. the journal of antibiotics, 1980, 33(8): 900-901.[3] janiak a m, milewski s. mechanism of antifungal action of kanosamine[j]. medical mycology, 2001, 39(5): 401-408.

Check Digit Verification of cas no

The CAS Registry Mumber 57649-10-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,6,4 and 9 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 57649-10:
(7*5)+(6*7)+(5*6)+(4*4)+(3*9)+(2*1)+(1*0)=152
152 % 10 = 2
So 57649-10-2 is a valid CAS Registry Number.

57649-10-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R,3S,4S,5R)-3-amino-2,4,5,6-tetrahydroxyhexanal,hydrochloride

1.2 Other means of identification

Product number -
Other names EINECS 260-881-4

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:57649-10-2 SDS

57649-10-2Upstream product

57649-10-2Downstream Products

57649-10-2Relevant academic research and scientific papers

Method for stabilizing proteins with saccharide linked protein polymer conjugates

-

, (2008/06/13)

A method is disclosed for preparing water soluble protein polymer conjugates which stabilize the protein so as to retain functional properties in a hostile environment. The method comprises covalently bonding the polymer to the protein through at least three linkers which linkers have three or more hydroxyl groups. The protein is conjugated at lysines or arginines.

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