5766-36-9

Upstream product

• 34589-46-3 (2,4-dimethylphenyl)magnesium bromide 
• 108-38-3 m-xylene 
• 298-12-4 Glyoxilic acid 
• 873385-13-8 2,4,2',4'-tetramethyl-benzhydryl chloride 
• 21945-76-6 bis(2,4-dimethylphenyl)methanol 
• 20809-72-7 Methyl-2,2-bis-<2,4-dimethyl-phenyl>-3-oxo-succinat 
• 106715-63-3 3,3-bis-(2,4-dimethyl-phenyl)-thietan-2-one 
• 860538-30-3 bis-(2,4-dimethyl-phenyl)-acetonitrile 

Downstream Products

• 3478-88-4 2,2',4,4'-tetramethylbenzophenone 

Relevant academic research and scientific papers

Taming of superacids: PVP-triflic acid as an effective solid triflic acid equivalent for Friedel-Crafts hydroxyalkylation and acylation

The application of poly(4-vinylpyridine) supported trifluoromethanesulfonic acid (PVP-TfOH, 1:10) as a convenient solid superacid catalyst system in Friedel-Crafts reactions is described. In the presence of PVP-TfOH, one pot solvent-free synthesis of a wide variety of diarylacetic acid derivatives was achieved by Friedel-Crafts hydroxyalkylation reaction of glyoxylic acid with arenes under mild conditions. Acylation of both activated and deactivated aromatic compounds with acetyl chloride was also achieved using PVP-TfOH complex under solvent-free conditions at room temperature. As the polymer supported triflic acid was found to be a very efficient and an easy-to-handle solid acid, it can be a useful addition to environmentally more adaptable strong acid catalyst systems.

Silica sulfuric acid as a highly efficient catalyst for the synthesis of diarylacetic acids

ABSTRACT: An efficient heterogeneous method for the synthesis of diarylacetic acids was developed utilizing silica sulfuric acid as a catalyst. The reaction is highly efficient with a small amount of catalyst for the combination of a variety of electron-n