57666-10-1

Upstream product

• 120-72-9 indole 
• 623-73-4 diazoacetic acid ethyl ester 
• 603-76-9 1-methylindole 

Downstream Products

• 96450-45-2 (1-Methyl-3-p-tolylazo-1H-indol-2-yl)-acetic acid ethyl ester 
• 98294-44-1 [3-(4-Chloro-phenylazo)-1-methyl-1H-indol-2-yl]-acetic acid ethyl ester 
• 98294-43-0 [3-(4-Methoxy-phenylazo)-1-methyl-1H-indol-2-yl]-acetic acid ethyl ester 
• 98294-45-2 [1-Methyl-3-(4-nitro-phenylazo)-1H-indol-2-yl]-acetic acid ethyl ester 
• 96450-44-1 ethyl 1-methyl-3-phenylazoindol-2-ylacetate 
• 104703-16-4 Ethyl 2-(3-Benzoyl-1-methylindole)acetate 
• 104703-23-3 4-Acetoxy-3-acetyl-1-p-chlorophenyl-6-methyl-3H<1,2>diazepino<5,6-d>indole 
• 98294-50-9 5-Methyl-2-(4-nitro-phenyl)-2,5-dihydro-pyridazino[4,3-b]indol-3-one 
• 104703-21-1 1-p-Chlorophenyl-4,5-dihydro-6-methyl-4-oxo-3H<1,2>diazepino<5,6-d>indole 
• 98294-48-5 2-(4-Methoxy-phenyl)-5-methyl-2,5-dihydro-pyridazino[4,3-b]indol-3-one 
• 98294-49-6 2-(4-Chloro-phenyl)-5-methyl-2,5-dihydro-pyridazino[4,3-b]indol-3-one 
• 96450-43-0 5-Methyl-2-p-tolyl-2,5-dihydro-pyridazino[4,3-b]indol-3-one 
• 96450-42-9 5-methyl-3-oxo-2-phenyl-2,3-dihydropyridazino<4,3-b>indole 
• 104703-20-0 4,5-Dihydro-6-methyl-4-oxo-1-phenyl-3H<1,2>diazepino<5,6-d>indole 

Relevant academic research and scientific papers

Tridentate Nickel(II)-Catalyzed Chemodivergent C-H Functionalization and Cyclopropanation: Regioselective and Diastereoselective Access to Substituted Aromatic Heterocycles

A Schiff-base nickel(II)-phosphene-catalyzed chemodivergent C-H functionalization and cyclopropanation of aromatic heterocycles is reported in moderate to excellent yields and very good regioselectivity and diastereoselectivity. The weak, noncovalent interaction between the phosphene ligand and Ni center facilitates the ligand dissociation, generating the electronically and coordinatively unsaturated active catalyst. The proposed mechanisms for the reported reactions are in good accord with the experimental results and theoretical calculations, providing a suitable model of stereocontrol for the cyclopropanation reaction.