57669-32-6

Upstream product

• 491-38-3 1-benzopyran-4(4H)-one 
• 14386-66-4 2-(formylacetyl)phenol 
• 39079-62-4 chromone-3-carboxylic acid 
• 118-93-4 o-hydroxyacetophenone 
• 109-94-4 formic acid ethyl ester 

Downstream Products

• 89814-15-3 3-(2-Hydroxy-phenyl)-3-[(E)-methoxyimino]-propionaldehyde O-methyl-oxime 
• 65479-04-1 5,5-<3-(2'-hydroxyphenyl)-isoxazolinyl>-hydroxylamine 
• 21834-60-6 3,4-dihydro-2H-1-benzopyran-3-ol 
• 491-38-3 1-benzopyran-4(4H)-one 
• 14386-66-4 2-(formylacetyl)phenol 
• 87059-79-8 ω-formyl-2'-hydroxyacetophenone 
• 66665-80-3 2-hydroxy-ω-formylacetophenone aldoxime 
• 66665-81-4 1-(2'-hydroxyphenyl)-propane-1,3-dione-1,3-dioxime 
• 241488-10-8 3-(2-Hydroxy-phenyl)-3-oxo-propionaldehyde O-methyl-oxime 

Relevant academic research and scientific papers

One-pot synthesis of 3-(furan-2-yl)-4: H -chromen-4-ones from 1-(2-hydroxyphenyl)butane-1,3-diones and 2,5-dimethoxy-2,5-dihydrofuran catalyzed via K10 montmorillonite under solvent-free conditions

A new, concise and efficient method of one-pot synthesis of 3-(furan-2-yl)-4H-chromen-4-ones was developed using K10 montmorillonite catalysis under solvent-free conditions. The procedure of the synthesis of 3-(furan-2-yl)-4H-chromen-4-ones was that 1-(2-hydroxyphenyl)butane-1,3-diones and 2,5-dimethoxy-2,5-dihydrofuran underwent a process of α-alkoxyalkylation in the presence of K10 montmorillonite at 80 °C for 0.5 h and continuously at 120 °C for another 0.5 h. The advantages of this method were that it was solvent-free, the K10 montmorillonite was recyclable and it had an easy work-up.

Benzopyrans : Part 40 - Alumina mediated transformations of 4-oxo-4H-1- benzopyran-3-carbaldehyde, -3-carboxylic acid and their 2-methylhomologues

In contact with alumina, the title aldehyde 1 (R = H, Me, Cl) gives the chromones 5 and 9,12 whereas the acid 2 affords the chromones 7, 10 and acetophenone 23. Alumina converts the aldehyde 3 to the xanthone 14, and the corresponding acid 4 to the chromone 8 and diketone 24.

ALKALINE DEGRADATION OF PARENT CHROMONOID COMPOUNDS (CHROMONE, FLAVONE, ISOFLAVONE)

Ring-opening and degradation processes of parent flavonoid compounds under alkaline conditions have been studied by means of thin-layer chromatography.The direction of the splitting has been found dependent on the OH(1-) ion concentration.In the case of isoflavone salicylic acid was present in the reaction mixture, indicating a novel type of degradation of isoflavonoids.