57674-20-1

Usage

Uses

Used in Food Industry:
2-chloro-3-(1-methylethyl)pyrazine is used as a flavoring agent for its nutty and earthy odor, enhancing the taste and aroma of various food products.
Used in Fragrance and Perfume Industry:
2-chloro-3-(1-methylethyl)pyrazine is used as a component in the manufacturing of fragrances and perfumes, contributing to their unique scents and long-lasting effects.
Used in Research and Development:
2-chloro-3-(1-methylethyl)pyrazine is utilized in scientific studies to explore its potential biological activities, such as antimicrobial and insecticidal properties, for various applications in different industries.

InChI:InChI=1/C7H9ClN2/c1-5(2)6-7(8)10-4-3-9-6/h3-5H,1-2H3

Upstream product

• 25680-59-5 2-hydroxy-3-isopropyl-pyrazine 
• 25680-59-5 3-isopropyl-1H-pyrazin-2-one 

Downstream Products

• 25773-40-4 2-Isopropyl-3-methoxypyrazine 

Relevant academic research and scientific papers

New insights into the synthesis and characterization of 2-methoxy-3-alkylpyrazines and their deuterated isotopologues

A previously described synthetic route for preparation of 2-methoxy-3-alkylprazines (MPs) based on condensation of glyoxal with an α-amino acid amide, followed by methylation with iodomethane yields 3-alkyl-1-methyl-1H-pyrazin-2-ones (N-methyl derivatives), rather than the designated 2-methoxy-3-alkylpyrazines (O-methyl derivatives). Despite similar nuclear magnetic resonance and mass spectral properties, gas chromatographic (GC) retention indices differ significantly, indicating chemical difference. With the example of 3-sec-butyl-1-methyl-1H-pyrazin-2-one and its 3-sec-butyl-1-[2H3]methyl-1H-pyrazin-2-one isotopologue, the position of the methyl group introduced could be assigned unambiguously, using heteronuclear multiple bond correlation (HMBC) NMR experiments. For future characterization, the spectroscopic (NMR, EI+MS) as well as GC retention index data on two stationary phases of the most aroma relevant MPs and their deuterated isotopologues are summarized. Copyright