57677-55-1

Upstream product

• 24850-33-7 allyltributylstanane 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 106-95-6 allyl bromide 
• 1730-25-2 allylmagnesium bromide 
• 2622-05-1 allylmagnesium bromide 

Downstream Products

• 1242076-98-7 (E)-5-(3-azidobut-1-enyl)-1,2,3-trimethoxybenzene 
• 1242077-08-2 (E)-4-phenyl-1-(4-(3,4,5-trimethoxyphenyl)but-3-en-2-yl)-1H-1,2,3-triazole 
• 1280224-74-9 (E)-4-methyl-N-(4-(3,4,5-trimethoxyphenyl)but-3-en-2-yl)benzenesulfonamide 
• 1449789-86-9 4-(2-bromophenyl)-1-(3,4,5-trimethoxyphenyl)butan-1-one 
• 1449789-92-7 4-(2-bromo-5-methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)butan-1-one 
• 1449789-96-1 4-(2-bromophenyl)-1-(3,4,5-trimethoxyphenyl)butan-1-ol 
• 1449790-02-6 4-(2-bromo-5-methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)butan-1-ol 
• 1449790-21-9 2-allyl-2-(1,3-benzodioxol-5-yl)chromane 
• 1449790-32-2 C₂₀H₂₄O₅ 
• 2653-46-5 allyl 4-methylbenzoate 
• 200616-99-5 1-(3,4,5-Trimethoxy-phenyl)-but-3-en-1-one 

Relevant academic research and scientific papers

Regioselective Synthesis of Arylsulfonyl Benzophenones via Aerobic Oxidative [3+3] Benzannulation Reactions

Regioselective synthesis of 3-arylsulfonyl benzophenone derivatives via base mediated, aerial-oxidative [3+3] benzannulation of α,β-unsaturated aldehydes and 4-sulfonyl butenones is reported. A variety of readily available acyclic building blocks are tran

Stereoselective Barbier-Type Allylations and Propargylations Mediated by CpTiCl3

CpTiCl2, prepared in situ by manganese reduction of CpTiCl3, is an excellent new system for the Barbier-type allylation and propargylation of carbonyl compounds. It can be used in catalytic amounts when combined with Et3N·HBr/TMSBr, which acts as a regenerating system. The high regio- and stereoselectivity shown by this system makes it useful for prenylation and crotylation processes in the synthesis of natural products.

Synthetic Studies Towards the Synthesis of 6-Substituted 3-Fluoro-5,6-dihydropyran-2-ones 1

The synthesis of 6-substituted 3-fluoro-5,6-dihydropyran-2-ones under mild conditions is described. The key step of the synthesis involves a Julia-Kocienski olefination.

Oxime-mediated oxychlorination and oxybromination of unactivated olefins

An oxime-mediated oxychlorination and oxybromination of unactivated olefins relying on palladium catalysis has been developed. A wide range of chlorinated and brominated isoxazolines has been synthesized in moderate to good yields. To demonstrate the value of the method, the brominated isoxazoline has been further converted to other useful synthetic feedstock.

Palladium-catalyzed allylic esterification via C-C bond cleavage of a secondary homoallyl alcohol

Palladium-catalyzed allylic esterifications of secondary homoallyl alcohols with acids via sequential retro-allylation and esterification are demonstrated, affording the corresponding allyl ester in up to 99% yield. The electron effect of the substituent of the secondary alcohol was found to be crucial to the selective C-C bond cleavage.

Oxime-mediated facile access to 5-methylisoxazoles and applications in the synthesis of valdecoxib and oxacillin

A palladium-catalyzed efficient synthesis of 5-methylisoxazoles via oxime-mediated functionalization of unactivated olefins is described. The reaction affords a variety of 5-methylisoxazoles in moderate to good yields. To further demonstrate the utility of the method, the rapid synthesis of valdecoxib and oxacillin is reported. (Chemical Equation Presented).

Transition metals catalyzed C-C and C-O bonds formation: Facile synthesis of flavans and benzoxepines

A simple and practical method has been developed based on intermolecular [Pd]-catalyzed C-C and an intramolecular [Cu]-catalyzed C-O bond formations for the synthesis of flavans and benzoxepines. Interestingly, the method is amenable for the synthesis of

Efficient,highly diastereoselective MS 4 A-promoted one-pot,three-component synthesis of 2,6-disubstituted-4- tosyloxytetrahydropyrans via Prins cyclization

A simple,efficient and highly diastereoselective one-pot three-component synthesis of functionalized 2,6-disubstituted-4-tosyloxytetrahydropyrans was performed. The synthesis features an optimized Prins cyclization in which an aromatic homoallylic alcohol

Lanthanum trichloride: A simple and efficient catalyst for allylation of aldehydes with allyltributylstannane

Aldehydes undergo smooth nucleophilic addition with allyltributyl-stannane in the presence of lanthanum trichloride to afford the corresponding homoallylic alcohols in excellent yields. All the reaction conditions were carried out in acetonitrile solvent at room temperature. In all the cases, the catalyst was used in a catalytic amount (10% mol). Copyright Taylor & Francis Group, LLC.

Potassium dodecatungsto cobaltate trihydrate: A new heterogeneous catalyst for the synthesis of homoallylic alcohols and amines

A simple and efficient procedure has been developed for one-pot synthesis of homoallylic alcohols and amines in good to excellent yields using a variety of aldehydes, amines, and allyltributylstannane in the presence of a catalytic amount of potassium dod