57685-13-9

Upstream product

• 108-24-7 acetic anhydride 
• 19246-50-5 9-hydroxycarbotanacetone 

Downstream Products

• 140860-29-3 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid 2-((1R,3S,4R)-3-hydroxy-4-methyl-cyclohexyl)-propyl ester 
• 140860-28-2 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid 2-((1R,3S,4R)-3-acetoxy-4-methyl-cyclohexyl)-propyl ester 

Relevant academic research and scientific papers

BIOTRANSFORMATION OF MONOTERPENOIDS, (-)- AND (+)-MENTHOLS, TERPINOLENE AND CARBOTANACETONE BY ASPERGILLUS SPECIES

Four monoterpenoids, (-)- and (+)-menthols, terpinolene and carvotanacetone were biotransformed by Aspergillus niger and several related species.Aspergillus niger converted (-)-menthol to 1-, 2-, 6-, 7-, and 9-hydroxymenthols and the mosquito repellent-active 8-hydroxymenthol.On the other hand, (+)-menthol was smoothly biotransformed by A. niger to give 7-hydroxymenthol.Aspergillus cellulosae biotransformed (-)-menthol specifically to 4-hydroxymenthol.Terpinolene and (-)-carvotanacetone were converted by A. niger to two α,β-unsaturated ketones, a fenchane-type compound and diastereoisomeric p-menthane-2,9-diols and 8-hydroxycarvomenthol, respectively.Key Word Index: Aspergillus awamori; A. cellulosae; A. fumigatus; A. niger; A. sojae; A. terreus; A. usami; Aspergillaceae; biotransformation; (-)- and (+)-menthols; terpinolene; (-)-carvotanacetone; mosquito repellent.