57689-65-3Relevant academic research and scientific papers
ETUDE DE LA REACTIVITE D'YLIDENEOXAZOLINE-5-ONES VIS-A-VIS DE COMPOSES ENAMINOCARBONYLES.
Maquestiau, A.,Vanden Eynde, J.-J.,Papleux, P.
, p. 849 - 858 (2007/10/02)
Reactions between 4-ylideneoxazolin-5-ones and enaminocarbonyl compounds do not lead to 4,7-dihydrooxazolopyridines.These reactions yield, by cleavage of the five-membered ring, monocyclic derivatives whose structures are elucidated.Thus, starting from 4-arylideneoxazolin-5-ones, mixtures of cis and trans dihydro-α-pyridones are formed but, in most cases, only the cis isomers can be isolated.Starting from 2-phenyl-4-ethoxymethyleneoxazolin-5-one, reactions proceed, in addition, by loss of ethanol and α-pyridones are obtained.
3,6-Diamino-3,4-dihydro-2-pyridones
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, (2008/06/13)
3,6-Diamino-3,4-dihydro-2-pyridones of the formula SPC1 Wherein R1 is straight or branched chain alkyl or alkenyl or said alkyl or alkenyl interrupted by 1 or 2 oxygen atoms; R2 is straight or branched chain alkyl; alkenyl; alkynyl; cycloalkyl; cycloalkenyl; cycloalkynyl; aryl unsubstituted or substituted by 1 to 3 of the same or different substituents selected from the group consisting of alkyl, alkoxy, halogen, nitro, cyano, trifluoromethyl, carbalkoxy and SOn -alkyl wherein n is 0 to 2; naphthyl; quinolyl; isoquinolyl; pyridyl, pyrimidyl, thienyl; or furyl; and R3 is straight or branched chain alkyl; or aryl unsubstituted or substituted by alkyl, alkoxy, nitro, trifluoromethyl or halo; Are produced by reacting a 4-ylidene-1,3-oxazoline-5-one of the formula SPC2 Wherein R2 and R3 are as above defined, with an amidinoacetic acid ester of the formula EQU1 or a salt thereof, WHEREIN R1 is as above defined, In the presence of an inert inorganic solvent and either in the presence of or in the absence of a catalytic amount of an alkali alcohol at a temperature of from about 20° C to about 200° C.
