57694-36-7

Usage

Uses

Used in Organic Synthesis:
2,3-diphenylthiirane is used as an intermediate in organic synthesis for the production of various pharmaceuticals, agrochemicals, and other organic compounds. Its unique structure and properties make it a versatile building block in the synthesis of complex organic molecules.
Used in Pharmaceutical Research:
In pharmaceutical research, 2,3-diphenylthiirane is utilized as a key component in the development of new drugs. Its potential applications in materials science and as a precursor for the synthesis of bioactive molecules contribute to its significance in this field.
Used in Materials Science:
2,3-diphenylthiirane has been studied for its potential applications in materials science, where it could be used to create novel materials with specific properties.
Used in Antimicrobial Applications:
2,3-diphenylthiirane has been investigated for its potential biological activities, including antifungal and antibacterial properties, making it a candidate for use in antimicrobial agents and treatments.

Upstream product

• 1689-71-0 2,3-diphenyloxirane 
• 1439-07-2 trans-Stilbene oxide 
• 63578-71-2 Thiophosphoric acid O,O'-diethyl ester S-(2-oxo-1,2-diphenyl-ethyl) ester 
• 343597-58-0 2,4-diphenyl-1,3-oxathiolan-5-one 
• 588-59-0 stilbene 
• 140-89-6 potassium ethyl xanthogenate 
• 1439-07-2 (S,S)-trans-stilbene oxide 
• 62533-71-5 trans-2-Methylimino-4,5-diphenyl-1,3-oxathiolan 
• 352564-79-5 C₂₁H₁₅NO₂S 
• 31247-20-8 α,α'-dibromodibenzyl sulfide 

Downstream Products

• 103-30-0 (E)-1,2-diphenyl-ethene 
• 22020-90-2 1,2-diphenylthiirane-S,S-dioxide 
• 645-49-8 cis-stilben 
• 34013-59-7 trans-stilbene episulphoxide 
• 128881-53-8 cis-5,6-diphenyl-1,2,3,4-tetrathiane 
• 128881-53-8 trans-5,6-diphenyl-1,2,3,4-tetrathiane 
• 6052-46-6 (Z)-(1,2-diphenylvinyl)(phenyl)sulfane 

Relevant academic research and scientific papers

Synthesis of Deuterated (E)-Alkene through Xanthate-Mediated Hydrogen-Deuterium Exchange Reactions

Herein we have developed a reversible hydrogen-deuterium exchange reaction of nonactivated olefins. By using EtOCS2K as a mediator, the H/D exchange reaction was realized through repeated addition and elimination reactions, demonstrating reversible H/D exchange between ordinary olefins and deuterated olefins. Using the lowest cost D2O without precious metal catalysts and ligands, a broad spectrum of compatibility of functional groups was achieved.

Mild and efficient desulfurization of thiiranes with MoCl5/Zn system

Desulfurization of a variety of thiiranes to alkenes occurs chemoselectively in high yields upon treatment with MoCl5/Zn system under mild conditions. The new methodology demonstrates high functional group tolerance toward chloro, bromo, fluoro, methoxy, ester, ether and keto groups.

Convenient synthesis of 1,3-dithiolane-2-thiones: Cyclic trithiocarbonates as conformational locks

A series of novel 1,3-dithiolane-2-thiones, or cyclic trithiocarbonates, has been prepared by a new simple procedure: a treatment of the corresponding epoxides with the commercially available potassium ethyl xanthogenate, KSC(S)OEt. The stereochemistry of the products was determined by 1H NMR and in some cases by single-crystal X-ray data. Cyclohexane-based 1,3- dithiolane-2-thiones revealed a trans-fusion of the carbo- and hetero-cycles. The products obtained from the mono-substituted cyclohexene oxides demonstrated an axial position of the substituents. Thus the epoxide transformation into trithiocarbonate can be used as a method for locking cyclic compounds in unstable conformations.ARKAT-USA, Inc.

Green synthesis of thiiranes from oxiranes under solvent- and catalyst-free conditions

A simple and efficient method for the conversion of oxiranes to thiiranes using ammonium thiocyanate (NH4SCN) under solvent- and catalyst-free conditions is described. These conditions enable clean and fast conversion of oxiranes to the corresponding thiirane.

Zeolite molecular sieve 4: A reusable catalyst for fast and efficient conversion of epoxides to thiiranes with thiourea

Various epoxides are readily converted to their corresponding thiiranes by thiourea/zeolite molecular sieve 4 system in refluxing MeOH. All reactions were carried out within 12-25 min to give thiiranes in 80%-99% yields. The catalyst saves its catalytic activity for several times at this transformation. Stereospecific conversion of (R)-(+)-styrene oxide to (S)-(+)-styrene episulfide was achieved by this combination system. Taylor & Francis Group, LLC.

A practical and eco-friendly method for conversion of epoxides to thiiranes with immobilized thiourea on CaCO3

Solvent-free conversion of various epoxides to the corresponding thiiranes was carried out efficiently with immobilized thiourea on CaCO3. The reactions were completed within 1-12 min under oil bath (60 °C-70 °C) conditions to afford thiiranes in 88%-98% yields. Copyright Taylor & Francis Group, LLC.

A green protocol for solvent-free conversion of epoxides to thiiranes with Dowex-50WX8-supported thiourea

Structurally different epoxides were efficiently converted to the corresponding thiiranes by Dowex-50WX8-supported thiourea under solvent-free conditions. The reactions were carried out either in an oil bath or under microwave irradiation to give the thiiranes in 75-98% yields within 30 sec-120 min.

Solvent-free conversion of epoxides to thiiranes by thiourea/NH4Cl system

Epoxides were readily converted to the corresponding thiiranes by thiourea/NH4Cl system under solvent-free conditions. The reactions were completed within 15-75 min at 60-70°C. The thiiranes were obtained in 65-96% yields. Copyright Taylor & Francis Group, LLC.

A facile and efficient one-pot synthesis of thiirans by the reaction of benzoxazolyl β-ketosulfides with NaBH4/NaOH

Convenient and efficient procedures for thiirans have been developed via a one-pot reaction of benzoxazolyl β-ketosulfides with NaBH4 and NaOH in MeOH and THF. The reaction is considered to proceed via the spiro intermediate by the ipso-additio

Iodine as a mild, efficient, and cost-effective catalyst for the synthesis of thiiranes from oxiranes

We developed an efficient protocol for the synthesis of thiiranes from oxiranes using a catalytic amount of molecular iodine. The notable features of this procedure are mild reaction conditions, high conversions, short reaction times, economic viability o