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4-CYANO-4-(3-FLUOROPHENYL)CYCLOHEXANONE is a cyclohexanone derivative with the molecular formula C13H13NO, featuring a cyano and fluorophenyl substituent. It is a versatile chemical compound used in organic synthesis and pharmaceutical research as a building block for creating various biologically active molecules. Its unique structural features contribute to its utility in the preparation of pharmaceuticals, agrochemicals, and other fine chemicals. Furthermore, it holds potential in the field of medicinal chemistry and drug discovery due to its pharmacological properties and biological activities.

577036-07-8

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577036-07-8 Usage

Uses

Used in Organic Synthesis:
4-CYANO-4-(3-FLUOROPHENYL)CYCLOHEXANONE is used as a building block in organic synthesis for the creation of various biologically active molecules. Its structural features make it a valuable intermediate in the synthesis process.
Used in Pharmaceutical Research:
In Pharmaceutical Research, 4-CYANO-4-(3-FLUOROPHENYL)CYCLOHEXANONE is utilized as a key intermediate for the development of new pharmaceuticals. Its unique properties allow for the exploration of its potential in treating various medical conditions.
Used in Medicinal Chemistry:
4-CYANO-4-(3-FLUOROPHENYL)CYCLOHEXANONE is employed in medicinal chemistry for its pharmacological properties and biological activities. It serves as a promising candidate for drug discovery, contributing to the advancement of new therapeutic agents.
Used in Agrochemicals:
In the Agrochemicals industry, 4-CYANO-4-(3-FLUOROPHENYL)CYCLOHEXANONE is used as a component in the synthesis of various agrochemical products, potentially enhancing crop protection and yield.
Used in Fine Chemicals:
4-CYANO-4-(3-FLUOROPHENYL)CYCLOHEXANONE is also utilized in the production of fine chemicals, where its unique structure and properties are leveraged to create high-quality specialty chemicals for various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 577036-07-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,7,7,0,3 and 6 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 577036-07:
(8*5)+(7*7)+(6*7)+(5*0)+(4*3)+(3*6)+(2*0)+(1*7)=168
168 % 10 = 8
So 577036-07-8 is a valid CAS Registry Number.

577036-07-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(3-fluorophenyl)-4-oxocyclohexane-1-carbonitrile

1.2 Other means of identification

Product number -
Other names 1-cyano-1-(3-fluorophenyl)cyclohexan-4-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:577036-07-8 SDS

577036-07-8Upstream product

577036-07-8Downstream Products

577036-07-8Relevant academic research and scientific papers

PHARMACEUTICAL COMPOUNDS

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, (2018/04/26)

This invention relates to compounds that are agonists of the muscarinic M1 receptor or M1 and M4 receptors and which are useful in the treatment of muscarinic M1 or M1/M4 receptor mediated

SUBSTITUTED ISOQUINOLINES AND ISOQUINOLINONES AS RHO KINASE INHIBITORS

-

Page/Page column 72, (2010/01/30)

The invention relates to substituted isoquinoline and isoquinolinones of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.

DI(HETERO)ARYLCYCLOHEXANE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM

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Page/Page column 95, (2009/01/24)

The present invention relates to di(hetero)arylcyclohexane derivatives of the formula (I), in which Ar1, Ar2, R1 and R2 have the meanings indicated in the claims. The compounds of the formula (I) are valuable pharmaceutical active compounds which inhibit ATP-sensitive potassium channels in the heart muscle and are suitable, for example, for the treatment of disorders of the cardiovascular system such as arrhythmias or a decreased contractility of the heart, such as can occur, for example, in coronary heart disease, cardiac insufficiency or cardiomyopathies. In particular, they are suitable for the prevention of sudden cardiac death. The invention furthermore relates to processes and intermediates for the preparation of the compounds of the formula (I), their use and pharmaceutical compositions comprising them.

Potent bradykinin B1 receptor antagonists: 4-Substituted phenyl cyclohexanes

Su, Dai-Shi,Lim, John L.,Markowitz, M. Kristine,Wan, Bang-Lin,Murphy, Kathy L.,Reiss, Duane R.,Harrell, C. Meacham,O'Malley, Stacy S.,Ransom, Rick W.,Chang, Raymond S.L.,Pettibone, Douglas J.,Tang, Cuyue,Prueksaritanont, Thomayant,Freidinger, Roger M.,Bock, Mark G.

, p. 3006 - 3009 (2008/02/04)

Selective bradykinin (BK) B1 receptor antagonists have been shown to be antinociceptive in animal models and could be novel therapeutic agents for the treatment of pain and inflammation. Elucidation of the structure-activity relationships of the biphenyl moiety of the lead compound 1 provided a potent new structural class of BK B1 receptor antagonists.

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