57705-17-6Relevant academic research and scientific papers
One-pot synthesis of 3,5-disubstituted and polysubstituted phenols from acyclic precursors
Qian, Jinlong,Yi, Wenbin,Huang, Xin,Miao, Yongbo,Zhang, Junkai,Cai, Chun,Zhang, Wei
supporting information, p. 1090 - 1093 (2015/03/14)
A new strategy for the synthesis of 3,5-disubstituted phenols is established through one-pot Robinson annulation of α,β-unsaturated ketones with α-fluoro-β-ketoesters followed by in situ dehydrofluorination and tautomerization. This method has been extended to the synthesis of polysubstituted phenols and applied in the preparation of biologically active compounds.
Ruthenium(II)-catalyzed synthesis of hydroxylated arenes with ester as an effective directing group
Yang, Yiqing,Lin, Yun,Rao, Yu
supporting information; experimental part, p. 2874 - 2877 (2012/07/28)
An unprecedented Ru(II) catalyzed ortho-hydroxylation has been developed for the facile synthesis of a variety of multifunctionalized arenes from easily accessible ethyl benzoates with ester as an efficient directing group. Both the TFA/TFAA cosolvent system and oxidants serve as the critical success factors in this transformation. The reaction demonstrates excellent reactivity, good functional group tolerance, and high yields.
Synthesis of dibenzo[b,d]pyran-6-ones based on a '[3+3] cyclization-Suzuki cross-coupling' strategy
Nguyen, Van Thi Hong,Langer, Peter
, p. 1013 - 1015 (2007/10/03)
Functionalized dibenzo[b,d]pyran-6-ones were prepared by sequential '[3+3] cyclization-Suzuki cross-coupling' reactions.
