57711-44-1Relevant articles and documents
Macrocyclic molecular rotors with bridged steroidal frameworks
Czajkowska-Szczykowska, Dorota,Rodriguez-Molina, Braulio,Magana-Vergara, Nancy E.,Santillan, Rosa,Morzycki, Jacek W.,Garcia-Garibay, Miguel A.
, p. 9970 - 9978 (2012)
In this work, we describe the synthesis and solid-state dynamics of isomeric molecular rotors 7E and 7Z, consisting of two androstane steroidal frameworks linked by the D rings by triple bonds at their C17 positions to a 1,4-phenylene rotator. They are also linked by the A rings by an alkenyl diester bridge to restrict the conformational flexibility of the molecules and reduce the number of potential crystalline arrays. The analysis of the resulting molecular structures and packing motifs offered insights of the internal dynamics that were later elucidated by means of line shape analyses of the spectral features obtained through variable-temperature solid-state 13C NMR; such analysis revealed rotations in the solid state occurring at kilohertz frequency at room temperature.
Catalyst-free and metal-free electrophilic bromoamidation of unactivated olefins using the N-bromosuccinimide/sulfonamide Protocol
Yu, Wesley Zongrong,Chen, Feng,Cheng, Yi An,Yeung, Ying-Yeung
, p. 2815 - 2821 (2015/03/18)
An efficient, catalyst-free, and metal-free bromoamidation of unactivated olefins has been developed. 4-(Trifluoromethyl)benzenesulfonamide and N-bromosuccinimide were used as the nitrogen and halogen sources, respectively. The methodology is applicable to both cyclic and aliphatic olefins.
First synthesis of a pentadeuterated 3′-hydroxystanozolol - An internal standard in doping analysis
Felzmann, Wolfgang,Gmeiner, Günter,G?rtner, Peter
, p. 103 - 110 (2007/10/03)
The first synthesis of 16,16,20,20,20-pentadeuterio-3′- hydroxystanozolol (8) in 26% yield over nine steps is described using moderately priced starting materials and economic amounts of reagents. Compound 8 can be used as an internal standard in screening procedures for anabolic steroids as well as for the quantification of stanozolol metabolites via mass spectrometric techniques, such as LC-MS or gas chromatography-mass spectrometry (GC-MS).