57738-11-1

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 8 carbon (C), 8 hydrogen (H), 2 nitrogen (N), 2 oxygen (O), and 1 sulfur (S) atoms.

Explanation

Due to its unique structure and properties, the compound may be useful in various fields, such as the synthesis of new organic compounds, development of pharmaceutical drugs, and creation of novel materials with specific properties.

Explanation

More studies and research are needed to fully understand the compound's potential applications, properties, and reactivity in different fields, as well as its safety and efficacy.

Explanation

The compound belongs to the class of heterocycles, which are organic compounds containing a ring of atoms with at least one heteroatom (atoms other than carbon and hydrogen). In this case, the heteroatoms are nitrogen, oxygen, and sulfur.

Explanation

The solubility of the compound is not provided, but it can be inferred that it may be soluble in polar solvents due to the presence of polar functional groups (ketones, thiazole, and imidazole).

Explanation

The stability of the compound is not provided, but it can be inferred that its stability may be influenced by the presence of the thiazole and imidazole rings, as well as the carbonyl group. Further research is needed to determine its stability under various conditions.

Explanation

The reactivity of the compound is not provided, but it can be inferred that its reactivity may be influenced by the presence of the ketone, thiazole, and imidazole functional groups. Further research is needed to determine its reactivity with other compounds and under different conditions.

Chemical Structure

Ketone derivative with a thiazole ring, an imidazole group, and a methyl substituent

Potential Applications

Organic synthesis, pharmaceuticals, and material science

Further Research

Required to explore potential uses and properties

Chemical Class

Heterocycles

Functional Groups

Ketone, thiazole, and imidazole

Solubility

Unknown, but may depend on the solvent's polarity

Stability

Unknown, but may be influenced by the compound's structure and functional groups

Reactivity

Unknown, but may be influenced by the compound's functional groups and structure

InChI:InChI=1/C8H8N2OS/c1-5-7(6(2)11)10-3-4-12-8(10)9-5/h3-4H,1-2H3

Upstream product

• 96-50-4 2-thiazolylamine 
• 72997-31-0 HacacBr 
• 3043-28-5 3-bromopentane-2,4-dione 
• 1694-29-7 3-chloropentane-2,4-dione 
• 72628-93-4 3-(1-acetyl-2-oxo-propyl)-2-amino-thiazolium; bromide 

Downstream Products

• 1116559-24-0 2-(4-bromophenyl)amino-4-(6-methylimidazo[2,1-b]thiazol-5-yl)-thiazole monohydrobromide 

Relevant academic research and scientific papers

HETEROCYCLIC COMPOUNDS AND USES AS ANTICANCER AGENTS

Novel compounds having a fused bicyclic heteroaromatic ring system substituted with a thiazole ring are disclosed. The compounds inhibit growth of a variety of types of cancer cells, and are thus useful for treating cancer. Efficacy of these compounds is demonstrated with a system for monitoring cell growth/migration, which shows they are potent inhibitors of growth and/or migration of cancer cells. In addition, compounds of the invention were shown to stop growth of tumors in vivo, and to reduce the size of tumors in vivo. Compositions comprising these compounds, and methods to use these compounds and compositions for treatment of cancers, are disclosed.

HETEROCYCLIC COMPOUNDS AND USES AS ANTICANCER AGENTS

Novel compounds having a fused bicyclic heteroaromatic ring system substituted with a heteroaryl five-membered ring are disclosed. The compounds inhibit growth of a variety of types of cancer cells, and are thus useful for treating cancer. Efficacy of these compounds is demonstrated with a system for monitoring cell growth/migration, which shows they are potent inhibitors of growth and/or migration of cancer cells. In addition, compounds of the invention were shown to stop growth of tumors in vivo, and to reduce the size of tumors in vivo. Compositions comprising these compounds, and methods to use these compounds and compositions for treatment of cancers, are disclosed.

Reaction of 2-Aminothiazoles with Reagents containing a C-Halogen and a C=O Electrophilic Centre

Seven reagents of different types having in common a C-Hal and a C=O electrophilic centre have been used in a study of their reactions with 2-aminothiazoles.Three reagents, CHBrAc2 and ROCHBrCO2Et (R = Me, Ph), gave imidazothiazoles, thus providing useful routes to the 5-acetyl and 5-ethoxycarbonyl derivatives.Unexpectedly, the solvent (acetone) was involved in the reaction of the fourth reagent, CHBr(CO2Et)2, with 2-aminothiazole which led to 5,5-di(ethoxycarbonyl)-6,6-dimethyl-5,6-dihydroimidazothiazole (yield 81percent).With the last three reagents (AcCHBrNO2, BzCHBrCN and ICH2CO2C6H4NO2-p) the outcome was simpler, viz., the formation of 2-amidothiazoles.It is proposed that electrophilic attack by the endo-N of the 2-aminothiazole is the first step in all cases.This occurs at the C-Hal centre of the first four reagents and is followed by cyclisation to the exo-N.In the last three electrophiles the presence of the groups well suited to leaving as stabilised anions favours addition to the C=O group; the intermediates so formed subsequently isomerise to the more stable exo-N substituted products.