57740-65-5Relevant academic research and scientific papers
Novel 3-aryl-2,5-dihydroxy-1,4-benzoquinone derivatives, their preparation method and pharmaceutical compositions containing same
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Page/Page column 4, (2008/06/13)
Compound of formula (I): wherein: R1 and R2, which may be identical or different, each represents hydrogen, acyl or alkyl, Ar represents aryl or heteroaryl, A represents a group selected from: R4 represents hydrogen or alk
Discovery of a potent, highly selective, and orally efficacious small-molecule activator of the insulin receptor
Liu,Xu,Szalkowski,Li,Ding,Kwei,Huskey,Moller,Heck,Zhang,Jones
, p. 3487 - 3494 (2007/10/03)
A series of 3,6-diaryl-2,5-dihydroxybenzoquinones were synthesized and evaluated for their abilities to selectively activate human insulin receptor tyrosine kinase (IRTK). 2,5-Dihydroxy-6-(1-methylindol-3-yl)-3-phenyl-1,4-benzoquinone (2h) was identified
Fungal Pigments, 49. - Synthesis of Grevillins and Related 2H-Pyran-2,5(6H)-diones
Lohrisch, Hans-Joachim,Kopanski, Lothar,Herrmann, Rupert,Schmidt, Holger,Steglich, Wolfgang
, p. 177 - 194 (2007/10/02)
A convergent synthesis of grevillins 1 starts from diazoesters 6 which are converted into 3-aryl-2-oxopropyl ethyl oxalates 4 via bromoketones 7.Cyclization of 4 leads to pyrandiones 2 which are condensed with aromatic aldehydes to yield 4-aryl-2-benzylid
