5775-13-3Relevant academic research and scientific papers
OXIDATION OF OLEFINS USING CHROMIC ANHYDRIDE-CHLOROTRIMETHYLSILANE. A CONVENIENT SYNTHESIS OF α-CHLORO KETONES.
Lee, Jong Gun,Ha, Dong Soo
, p. 193 - 196 (1989)
Disubstituted internal olefins are oxidized selectively to α-chloro ketones in excellent yields from the reaction with chromic anhydride-chlorotrimethylsilane in carbon tetrachloride.
Iron(iii) chloride hexahydrate-promoted selective hydroxylation and chlorination of benzyl ketone derivatives for the construction of hetero-quaternary scaffolds
Chen, Tao,Peng, Rui,Hu, Wenxin,Zhang, Fu-Min
supporting information, p. 9859 - 9867 (2016/10/31)
A novel and tunable α-hydroxylation/α-chlorination of benzyl ketone derivatives has been developed for the construction of hetero-quaternary carbon centers by iron(iii) chloride hexahydrate mediated selective transformations through the application of dif
Sulfoxide-mediated Umpolung of alkali halide salts
Klimczyk, Sebastian,Huang, Xueliang,Fares, Christophe,Maulide, Nuno
supporting information; experimental part, p. 4327 - 4329 (2012/06/29)
A new protocol for the direct two-electron oxidative Umpolung of alkali halide salts is reported. This procedure, relying on the use of a commercially available sulfoxide as the oxidant, allows the electrophilic halogenation of carbonyl compounds as well as halolactonisation reactions to proceed from the corresponding sodium salts, at room temperature and under mild conditions.
Enantioselective protonation of samarium enolates derived from α- heterosubstituted ketones and lactone by SmI2-mediated reduction
Nakamura, Yutaka,Takeuchi, Seiji,Ohgo, Yoshiaki,Yamaoka, Makoto,Yoshida, Akihiro,Mikami, Koichi
, p. 4595 - 4620 (2007/10/03)
SmI2-mediated reductive cleavage of α-heterosubstituents of α-alkyl or α-aryl ketones and lactone gave the corresponding 'thermodynamic samarium enolates'. Enantioselective protonation of the samarium enolates with C2- symmetric chiral diols afforded the corresponding ketones and lactone in moderate to high enantioselectivities.
